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老年患者减重手术的结局:一项当代、全国性分析。

Bariatric surgery outcomes in geriatric patients: a contemporary, nationwide analysis.

机构信息

Cardiovascular Outcomes Research Laboratories (CORELAB), David Geffen School of Medicine, University of California, Los Angeles, California.

David Geffen School of Medicine, University of California, Los Angeles, California.

出版信息

Surg Obes Relat Dis. 2022 Aug;18(8):1005-1011. doi: 10.1016/j.soard.2022.04.014. Epub 2022 Apr 22.

DOI:10.1016/j.soard.2022.04.014
PMID:35589528
Abstract

OBJECTIVE

This retrospective study sought to characterize the incidence of mortality in elderly patients following bariatric surgery and assessed the association of geriatric status with postoperative outcomes and resource use.

BACKGROUND

Bariatric surgery is a safe and efficacious intervention for obesity and related diseases. The clinical and economic impact of geriatric status on bariatric surgery is largely unexplored.

SETTING

Academic, university-affiliated hospital; US.

METHODS

Adults (≥45 yr) undergoing elective laparoscopic gastric bypass or sleeve gastrectomy were identified in the 2016-2019 Nationwide Readmissions Database. Patients ≥65 years were categorized into the geriatric cohort. Multivariable linear and logistic models were developed to evaluate the independent association of geriatric status with outcomes of interest.

RESULTS

Of an estimated number of 351,292 patients meeting inclusion criteria, 44,183 (12.6%) comprised the geriatric cohort. Of these patients, .3% died during the index hospitalization. Geriatric status was associated with significantly increased odds of in-hospital mortality (adjusted odds ratio [AOR] = 2.39, 95% confidence interval [CI]: 1.33-4.30), respiratory (AOR = 1.34, 95% CI: 1.13-1.59), infectious (AOR = 1.65, 95% CI: 1.25-2.17), and renal complications (AOR = 1.27, 95% CI: 1.12-1.46), and prolonged hospitalization (AOR = 1.35, 95% CI: 1.24-1.48). Elderly patients experienced a .19-day increment in the length of stay (95% CI: .11-.27) and $620 in attributable hospitalization costs (95% CI: 310-930).

CONCLUSIONS

While overall rates of postoperative death and complications are low, geriatric patients experience significantly increased mortality, morbidity, and resource use following bariatric operations relative to younger adults. These findings may aid in shared decision-making for obesity management in geriatric patients.

摘要

目的

本回顾性研究旨在描述肥胖症患者在接受减重手术后的死亡率,并评估老年状态与术后结局和资源利用的关系。

背景

减重手术是肥胖症及其相关疾病的一种安全有效的治疗方法。老年状态对减重手术的临床和经济影响在很大程度上尚未得到探索。

地点

学术型、大学附属医院;美国。

方法

在 2016 年至 2019 年全国再入院数据库中确定了接受择期腹腔镜胃旁路术或袖状胃切除术的成年人(≥45 岁)。≥65 岁的患者被归入老年组。采用多变量线性和逻辑模型评估老年状态与感兴趣结局的独立相关性。

结果

在符合纳入标准的估计 351292 名患者中,44183 名(12.6%)为老年组。这些患者中有 0.3%在住院期间死亡。老年状态与住院期间死亡率显著增加相关(调整后优势比 [AOR] = 2.39,95%置信区间 [CI]:1.33-4.30)、呼吸(AOR = 1.34,95% CI:1.13-1.59)、感染(AOR = 1.65,95% CI:1.25-2.17)和肾脏并发症(AOR = 1.27,95% CI:1.12-1.46),住院时间延长(AOR = 1.35,95% CI:1.24-1.48)。老年患者的住院时间增加了 0.19 天(95% CI:0.11-0.27),住院费用增加了 620 美元(95% CI:310-930 美元)。

结论

尽管术后死亡和并发症的总体发生率较低,但与年轻成年人相比,老年患者在接受减重手术后的死亡率、发病率和资源利用率显著增加。这些发现可能有助于老年肥胖症患者的管理决策。

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