针对 Epstein-Barr 病毒治疗多发性硬化症。
Targeting Epstein-Barr virus to treat MS.
机构信息
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115 USA.
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115 USA.
出版信息
Med. 2022 Mar 11;3(3):159-161. doi: 10.1016/j.medj.2022.02.005.
Epstein-Barr virus (EBV) is a putative trigger for multiple sclerosis (MS). Bjornevik et al. utilized longitudinal analysis of 10 million adults to strongly link MS to EBV infection and Lanz et al. identified clonally expanded B cells in MS that bind EBV EBNA1 and GlialCam..
爱泼斯坦-巴尔病毒（EBV）被认为是多发性硬化症（MS）的一个潜在触发因素。Bjornevik 等人利用对 1000 万成年人的纵向分析，强有力地将 MS 与 EBV 感染联系起来，而 Lanz 等人则在 MS 患者中发现了能结合 EBV EBNA1 和 GlialCam 的克隆性扩增 B 细胞。
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