Kim Hyunseok, Choi Tae-Lim
Department of Chemistry, Seoul National University, Seoul 151-747, Korea.
ACS Macro Lett. 2014 Aug 19;3(8):791-794. doi: 10.1021/mz5003239. Epub 2014 Jul 30.
Efficient synthesis of polyimidates has been a great challenge because of the difficulty of imidate bond formation and limited substrate scope. Here, we describe a successful method for the synthesis of various poly(-sulfonylimidates) using Cu-catalyzed multicomponent polymerization (MCP). Minimizing water contamination in the polymerization, which results in low-molecular-weight oligomers, allows various combinations of three types of monomers (diynes, sulfonyl azides, and diols) that are bench stable and readily accessible, providing access to a library of polyimidates. Moreover, the formation of polyimidates is highly selective over the conventional click reactions. Most importantly, this report demonstrates a successful MCP that overcomes the drawbacks of previous MCP methods showing narrow monomer scope and producing low-molecular-weight polymers.
由于亚胺酸酯键形成困难且底物范围有限，聚亚胺酸酯的高效合成一直是一个巨大的挑战。在此，我们描述了一种使用铜催化多组分聚合（MCP）合成各种聚（磺酰基亚胺酸酯）的成功方法。将聚合过程中的水污染降至最低，这会导致低分子量低聚物的产生，使得三种易于储存且易于获得的单体（二炔、磺酰叠氮化物和二醇）能够进行各种组合，从而获得一系列聚亚胺酸酯。此外，与传统的点击反应相比，聚亚胺酸酯的形成具有高度选择性。最重要的是，本报告展示了一种成功的MCP，它克服了以前MCP方法的缺点，即单体范围狭窄且生成低分子量聚合物。
