具有可控分子量、低分散指数和高转化率的聚（双（2,2,2-三氟乙氧基）磷腈）的稳健且操作简单的合成方法。

Robust and Operationally Simple Synthesis of Poly(bis(2,2,2-trifluoroethoxy) phosphazene) with Controlled Molecular Weight, Low PDI, and High Conversion.

作者信息

Steinke Joachim H G, Greenland Barnaby W, Johns Stephen, Parker Matthew P, Atkinson Robert C J, Cade Ian A, Golding Peter, Trussell Stephen J

机构信息

Department of Chemistry, Imperial College London, Exhibition Road, South Kensington, London, SW7 2AZ, United Kingdom.

Reading School of Pharmacy, University of Reading, Whiteknights, Reading, RG6 6 AU, United Kingdom.

出版信息

ACS Macro Lett. 2014 Jun 17;3(6):548-551. doi: 10.1021/mz500199x. Epub 2014 May 29.

DOI:10.1021/mz500199x

PMID:35590724

Abstract

Synthetically straightforward conditions have been developed for the preparation of poly(bis 2,2,2-trifluoroethoxy)phosphazene with low PDI (<1.15) at high conversion (75-99%) and on a multigram scale. A combination of P NMR and GPC analyses demonstrate that molecular weight increases linearly as a function of monomer consumption, exhibiting first order kinetics with respect to monomer concentration up to high monomer conversion. Thus, the molecular weight can be controlled by varying the initiator (HO) to monomer ratio.

摘要

已经开发出合成简单的条件，用于在高转化率（75-99%）下以多克规模制备具有低多分散指数（<1.15）的聚（双2,2,2-三氟乙氧基）磷腈。磷核磁共振（P NMR）和凝胶渗透色谱（GPC）分析相结合表明，分子量随单体消耗呈线性增加，在高单体转化率之前，相对于单体浓度呈现一级动力学。因此，可以通过改变引发剂（HO）与单体的比例来控制分子量。