School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Suzhou 215163, China.
Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Sensors (Basel). 2022 Apr 28;22(9):3368. doi: 10.3390/s22093368.
Motor function evaluation is a significant part of post-stroke rehabilitation protocols, and the evaluation of wrist motor function helps provide patients with individualized rehabilitation training programs. However, traditional assessment is coarsely graded, lacks quantitative analysis, and relies heavily on clinical experience. In order to objectively quantify wrist motor dysfunction in stroke patients, a novel quantitative evaluation system based on force feedback and machine learning algorithm was proposed. Sensors embedded in the force-feedback robot record the kinematic and movement data of the subject, and the rehabilitation doctor used an evaluation scale to score the wrist function of the subject. The quantitative evaluation models of wrist motion function based on random forest (RF), support vector machine regression (SVR), k-nearest neighbor (KNN), and back propagation neural network (BPNN) were established, respectively. To verify the effectiveness of the proposed quantitative evaluation system, 25 stroke patients and 10 healthy volunteers were recruited in this study. Experimental results show that the evaluation accuracy of the four models is all above 88%. The accuracy of BPNN model is 94.26%, and the Pearson correlation coefficient between model prediction and clinician scores is 0.964, indicating that the BPNN model can accurately evaluate the wrist motor function for stroke patients. In addition, there was a significant correlation between the prediction score of the quantitative assessment system and the physician scale score (p < 0.05). The proposed system enables quantitative and refined assessment of wrist motor function in stroke patients and has the feasibility of helping rehabilitation physicians in evaluating patients’ motor function clinically.
运动功能评估是脑卒中后康复方案的重要组成部分,腕部运动功能评估有助于为患者提供个体化的康复训练方案。然而,传统评估方法分级粗糙,缺乏定量分析,且严重依赖临床经验。为了客观量化脑卒中患者的腕部运动功能障碍,提出了一种基于力反馈和机器学习算法的新型定量评估系统。力反馈机器人中嵌入的传感器记录受试者的运动学和运动数据,康复医生使用评估量表对受试者的腕部功能进行评分。分别建立了基于随机森林(RF)、支持向量机回归(SVR)、k-最近邻(KNN)和反向传播神经网络(BPNN)的腕部运动功能定量评估模型。为了验证所提出的定量评估系统的有效性,本研究招募了 25 名脑卒中患者和 10 名健康志愿者。实验结果表明,四个模型的评估准确性均在 88%以上。BPNN 模型的准确性为 94.26%,模型预测与临床医生评分之间的皮尔逊相关系数为 0.964,表明 BPNN 模型可以准确评估脑卒中患者的腕部运动功能。此外,定量评估系统的预测评分与医生量表评分之间存在显著相关性(p<0.05)。该系统实现了对脑卒中患者腕部运动功能的定量和精细化评估,具有帮助康复医师临床评估患者运动功能的可行性。