Albeladi Fatma I, Wahby Salem Iman M, Albandar Albandari A, Almusaylim Hamidah A, Albandar Ali S
Internal Medicine Department (Nephrology), King Abdulaziz university, Faculty of Medicine, Family and Community Medicine, Rabigh, KSA.
Community and Occupational Medicine, Faculty of Medicine, Al Azhar University, Egypt.
J Taibah Univ Med Sci. 2021 Nov 20;17(2):256-263. doi: 10.1016/j.jtumed.2021.09.010. eCollection 2022 Apr.
Infectious diseases are the common cause of morbidity and mortality among humans. Electrolyte imbalance occurs frequently in patients with infectious diseases. This study aims to identify electrolyte imbalances in hospitalised patients with infectious diseases.
Two hundred and eighty-three patients with age mean 36.48 ± 18.86 years, consisting of 127 (53.4%) males, 111 (46.6%) females, enrolled in a retrospective cohort study carried out at the King Abdulaziz University Hospital, Jeddah, KSA from September to December 2020. All hospitalised patients with infectious diseases were included. Demographic data, comorbidity, and diagnosis were collected from patients' sheets. Serum levels of electrolytes (chloride, potassium, sodium), urea, and creatinine were collected at admission (period 1), during hospital stay (period 2), and at discharge (period 3). Levels were compared during different periods.
Most infectious diseases were viral infections (63.4%), while comorbidity was diabetes mellitus (7.1%). Serum chloride elevated from period 1 to period 3 (P = 0.046). Sodium elevated between period 1 and both period 2 and period 3 (P < 0.001). Urea decreased between period 1 and both period 2 (P = 0.018) and period 3 (P < 0.001). Creatinine decreased between period 1 and both period 2 and period 3 (P < 0.001) and between period 2 and period 3 (P < 0.001). Patients with decreased chloride and sodium levels were mostly in the 1st period, while those with decreased potassium levels were mostly in the period 2.
Prevalence of electrolyte imbalance in hospitalised patients with an infectious disease at the King Abdulaziz University Hospital, Jeddah was high, especially at admission and during the hospital stay.
传染病是人类发病和死亡的常见原因。电解质失衡在传染病患者中频繁发生。本研究旨在确定住院传染病患者的电解质失衡情况。
283例患者，平均年龄36.48±18.86岁，其中男性127例（53.4%），女性111例（46.6%），纳入2020年9月至12月在沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院进行的一项回顾性队列研究。纳入所有住院传染病患者。从患者病历中收集人口统计学数据、合并症和诊断信息。在入院时（第1阶段）、住院期间（第2阶段）和出院时（第3阶段）收集血清电解质（氯、钾、钠）、尿素和肌酐水平。比较不同阶段的水平。
大多数传染病为病毒感染（63.4%），而合并症为糖尿病（7.1%）。血清氯从第1阶段到第3阶段升高（P = 0.046）。钠在第1阶段与第2阶段和第3阶段均升高（P < 0.001）。尿素在第1阶段与第2阶段（P = 0.018）和第3阶段（P < 0.001）均降低。肌酐在第1阶段与第2阶段和第3阶段均降低（P < 0.001），且在第2阶段和第3阶段之间也降低（P < 0.001）。氯和钠水平降低的患者大多在第1阶段，而钾水平降低的患者大多在第2阶段。
吉达阿卜杜勒阿齐兹国王大学医院住院传染病患者电解质失衡的患病率较高，尤其是在入院时和住院期间。
