Alshaghel Mohammed Moutaz, Mayo Wafik, Sakkal Najeeb, Alali Kutaiba, Wereeki Mahmoud
Faculty of Medicine, University of Aleppo, Aleppo, Syria.
CME Office, Faculty of Medicine, University of Aleppo, Aleppo, Syria.
Ann Med Surg (Lond). 2022 May 11;78:103755. doi: 10.1016/j.amsu.2022.103755. eCollection 2022 Jun.
Choroid Plexus Carcinomas (CPC) are rare malignant brain neoplasms of choroid plexus epithelium, with a tendency to occur in infants and children, especially those who are under two years of age. The Main symptoms of CPC include nausea, vomiting, headache, irritability, blurred vision, and seizures. Few studies discuss the therapeutic methods to treat this tumor. However, most of these studies confirmed the poor prognosis of it.
A two-year-old girl presented with a headache due to head trauma, normal consciousness, GCS 15/15, and without intracranial hypertension symptoms. Computed Tomography (CT) has shown a large heterogeneous lesion in the region of the right lateral ventricle. Magnetic resonance imaging (MRI) showed a large poorly-defined mass in the right lateral ventricle with mild dilatation of the ipsilateral lateral ventricle, and midline shift and marked edema surrounding it. In this case, the mass has been discovered by accident. The histological diagnosis was choroid plexus carcinoma (WHO grade 3), curettage of the right lateral ventricle was performed.
CPC is a serious condition with a poor prognosis. Early diagnosis and appropriate approaches are required in order to reduce mortality and morbidity rates.