Insight Policy Research, Arlington, VA 22209, USA.
J Comp Eff Res. 2022 Jun;11(8):563-574. doi: 10.2217/cer-2021-0260. Epub 2022 May 20.
Among hospitalized patients, venous thromboembolism (VTE) is a preventable cause of morbidity and mortality. This study analyzed the effects of a large-scale adoption of a prompt response and education protocol to increase VTE prophylaxis adherence in the USA. A Markov model was developed that simulates outcomes and costs of delivering a VTE education bundle versus not, to hospitalized at-risk patients. The education bundle could avert more than 134,000 VTEs, 552,000 hospital days and 19,000 deaths over 5 years. Patients could save 13 million hours in work absenteeism and travel time, valued at US$237 million. Total societal savings could amount to US$2.8 billion. In scenario analyses with assumed lower-effectiveness estimates, the bundle averts 16,000 VTEs, 67,000 hospital days and 2000 deaths. A nationwide rollout of an education bundle to reduce missed doses of prescribed prophylaxis could improve quality of care, resulting in a decline in VTEs and mortality.
在住院患者中，静脉血栓栓塞症（VTE）是可预防的发病率和死亡率的原因。本研究分析了在美国大规模采用快速反应和教育方案来提高 VTE 预防措施依从性的效果。 开发了一个马尔可夫模型，模拟为有风险的住院患者提供 VTE 教育包与不提供的结果和成本。 在 5 年内，该教育包可避免超过 134,000 例 VTE、552,000 个住院日和 19,000 例死亡。患者可以节省 1300 万小时的旷工和旅行时间，价值 2.37 亿美元。全社会的储蓄可能达到 28 亿美元。在假设效果估计较低的情景分析中，该教育包可避免 16,000 例 VTE、67,000 个住院日和 2000 例死亡。 在全国范围内推出减少处方预防措施漏服的教育包可以改善护理质量，从而降低 VTE 和死亡率。
