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莱姆心炎合并多形性室性心动过速和心脏骤停:病例报告。

Lyme Carditis Complicated by Polymorphic Ventricular Tachycardia and Cardiac Arrest: A Case Report.

机构信息

Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, USA.

Department of Medicine, The University of Vermont Medical Center, Burlington, USA.

出版信息

J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221098333. doi: 10.1177/23247096221098333.

DOI:10.1177/23247096221098333
PMID:35593429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9125101/
Abstract

Lyme disease is commonly encountered in endemic areas of the United States harboring the causal organism . Lyme carditis can manifest in early disseminated infections, usually as atrioventricular nodal blockade. Timely antibiotic therapy typically suppresses myocardial inflammation and reverses cardiac conduction disturbances. We present a case of a previously healthy male who presented to the emergency department with non-prodromal syncope, multifocal annular rashes, and antecedent inflammatory knee pain and effusion, found to have positive 2-tier Lyme testing and pause-dependent polymorphic ventricular tachycardia leading to cardiac arrest. Lyme carditis occurs in early disseminated infections but rarely leads to cardiac arrest. Acute management is entrained in well-established guidelines for therapy, and together with risk stratification scoring can be considered by emergency care physicians in the workup of undifferentiated syncope with concern for Lyme disease with cardiac involvement.

摘要

莱姆病在美国的流行地区很常见,这些地区存在着致病生物。莱姆心炎可在早期播散性感染中表现出来,通常表现为房室结阻滞。及时的抗生素治疗通常可抑制心肌炎症并逆转心脏传导障碍。我们报告了一例既往健康的男性患者,他因非前驱性晕厥、多灶性环状皮疹、先前的炎性膝关节疼痛和积液而到急诊科就诊,检查发现 2 级莱姆病检测呈阳性,伴有依赖停顿的多形性室性心动过速导致心脏骤停。莱姆心炎发生在早期播散性感染中,但很少导致心脏骤停。急性管理遵循既定的治疗指南,并且可以由急诊医生在对疑似莱姆病合并心脏受累的非特异性晕厥进行评估时,结合风险分层评分进行考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f393/9125101/0d0b8eec87f4/10.1177_23247096221098333-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f393/9125101/44b5c6300057/10.1177_23247096221098333-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f393/9125101/d6a99dc34c60/10.1177_23247096221098333-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f393/9125101/0d0b8eec87f4/10.1177_23247096221098333-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f393/9125101/44b5c6300057/10.1177_23247096221098333-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f393/9125101/d6a99dc34c60/10.1177_23247096221098333-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f393/9125101/0d0b8eec87f4/10.1177_23247096221098333-fig3.jpg

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本文引用的文献

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Diagnosis and Treatment of Lyme Carditis: JACC Review Topic of the Week.莱姆心炎的诊断与治疗:美国心脏病学会杂志(JACC)本周专题
J Am Coll Cardiol. 2019 Feb 19;73(6):717-726. doi: 10.1016/j.jacc.2018.11.035.
2
Suspicious index in Lyme carditis: Systematic review and proposed new risk score.莱姆病性心肌炎的可疑指标:系统评价及新风险评分建议
Clin Cardiol. 2018 Dec;41(12):1611-1616. doi: 10.1002/clc.23102. Epub 2018 Nov 26.
3
Treating Lyme carditis high-degree AV block using a temporary-permanent pacemaker.使用临时-永久起搏器治疗莱姆病性心肌炎所致高度房室传导阻滞。
Ann Noninvasive Electrocardiol. 2019 May;24(3):e12599. doi: 10.1111/anec.12599. Epub 2018 Sep 28.
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Lyme carditis.莱姆病性心脏炎
Infect Dis Clin North Am. 2015 Jun;29(2):255-68. doi: 10.1016/j.idc.2015.02.003.
5
Lyme carditis--diagnosis, treatment and prognosis.莱姆病性心脏病——诊断、治疗与预后
Dtsch Arztebl Int. 2015 Mar 20;112(12):202-8. doi: 10.3238/arztebl.2015.0202.
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Borrelia burgdorferi (Lyme disease).伯氏疏螺旋体(莱姆病)。
Pediatr Rev. 2014 Dec;35(12):500-9. doi: 10.1542/pir.35-12-500.
7
[Cardiac arrest due to torsades de pointes ventricular tachycardia in a patient with Lyme carditis].[莱姆病性心肌炎患者发生尖端扭转型室性心动过速所致心脏骤停]
Ugeskr Laeger. 2014 Aug 25;176(35).
8
Transient prolonged corrected QT interval in Lyme disease.莱姆病中的短暂性校正QT间期延长
J Pediatr. 2006 May;148(5):692-7. doi: 10.1016/j.jpeds.2005.11.031.