异基因造血干细胞移植后移植物抗宿主病引起的口腔黏膜下纤维性变。
Oral submucous fibrosis induced by graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
机构信息
Department of Periodontics and Oral Medicine, Xiangya Stomatological Hospital & Xiangya School of Stomatology, Central South University & Hunan Key Laboratory of Oral Health Research & Hunan Clinical Research Center of Oral Major Diseases and Oral Health & Academician Workstation for Oral-maxillofacial and Regenerative Medicine, Changsha 410008, China.
Department of Periodontics and Oral Medicine, Xiangya Stomatological Hospital & Xiangya School of Stomatology, Central South University & Hunan Key Laboratory of Oral Health Research & Hunan Clinical Research Center of Oral Major Diseases and Oral Health & Academician Workstation for Oral-maxillofacial and Regenerative Medicine, Changsha 410008, China; Department of Oral Health Science, School of Dentistry, University of Washington, Seattle, WA 98195, USA.
出版信息
Oral Oncol. 2022 Jul;130:105919. doi: 10.1016/j.oraloncology.2022.105919. Epub 2022 May 17.
Graft-versus-host disease (GVHD) is one of the most common and serious complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT). About 45%∼83% of patients develop GVHD in the oral cavity. There has no medical records of oral submucous fibrosis (OSF) induced by GVHD after allo-HSCT, which should be brought to the attention of dentists.
移植物抗宿主病（GVHD）是异基因造血干细胞移植（allo-HSCT）后最常见和最严重的并发症之一。约 45%∼83%的患者会在口腔中发生 GVHD。allo-HSCT 后由 GVHD 引起的口腔黏膜下纤维化（OSF）在医学记录中尚无记载，这一点应该引起牙医的注意。
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