从人脑膜瘤来源的细胞培养物中分离井上-梅尔尼克病毒并检测脑膜瘤患者的抗体。
Isolation of Inoue-Melnick virus from human meningioma-derived cell cultures and detection of antibody in patients with meningioma.
作者信息
Inoue Y K, Nishibe Y, Hollinshead A C, Takeuchi J, Uchida Y, Handa H
出版信息
J Med Virol. 1987 Mar;21(3):201-5. doi: 10.1002/jmv.1890210302.
PMID:3559526
Abstract
Inoue-Melnick virus (IMV) was isolated from six of seven human meningioma-derived cell cultures, while the virus was not isolated from six other brain tumor cell cultures. Sera of 145 consecutive neurosurgical inpatients were tested for IMV-neutralizing antibody. Of 26 patients with meningioma, 22 were positive for IMV antibody (84.6%). Of the remaining 119 patients, 16 were positive.
摘要
井上-梅尔尼克病毒（IMV）从7种源自人脑膜瘤的细胞培养物中的6种中分离出来，而在其他6种脑肿瘤细胞培养物中未分离出该病毒。对145名连续神经外科住院患者的血清进行了IMV中和抗体检测。在26例脑膜瘤患者中，22例IMV抗体呈阳性（84.6%）。在其余119例患者中，16例呈阳性。
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