Department of Population Health, Dasman Diabetes Institute, Kuwait City, Kuwait.
Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Med Princ Pract. 2022;31(5):471-479. doi: 10.1159/000524756. Epub 2022 May 20.
Establishing a pediatric COVID-19 registry in Kuwait (PCR-Q8) was deemed imperative during the pandemic to study children infected with severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) focusing on mode of presentation, therapeutic interventions, disease severity, and early outcomes. This manuscript describes the rapid establishment of the PCR-Q8 registry showcasing an infrastructure of the development process and presents the results of the pilot phase.
The registry was developed and implemented using the general key steps from a resource titled "Registries for Evaluating Patient Outcomes: A User's Guide" as a guide for best practice, experience from a previously established pediatric diabetes registry in Kuwait and several other COVID-19 registries developed globally. During the pilot phase, a convenience sample of 120 children was included, of whom 66 (55%) were male.
Experience and expertise from other COVID-19 registries; guidance provided by the World Health Organization; and effective collaboration and cooperation between the stakeholders, study group, and data enterers during these challenging times were critical for the development and implementation of the registry. Our results were similar to international reports which showed that most children presented with mild disease (69.2%), majority (70.2%) had normal chest X-ray, and the most common symptom at presentation was fever (77%).
We anticipate the development of PCR-Q8 to be a stepping-stone for more in-depth investigation of SARS-CoV-2 infection in children in Kuwait and for the establishment of other registries.
在大流行期间，在科威特（PCR-Q8）建立一个儿科 COVID-19 登记处被认为是必要的，以便研究感染严重急性呼吸综合征相关冠状病毒 2（SARS-CoV-2）的儿童，重点关注发病模式、治疗干预、疾病严重程度和早期结局。本文描述了快速建立 PCR-Q8 登记处的过程，展示了发展过程的基础设施，并介绍了试点阶段的结果。
该登记处是使用一份名为“评估患者结局的登记册：使用指南”的资源中的一般关键步骤开发和实施的，该资源作为最佳实践的指南，借鉴了科威特以前建立的儿科糖尿病登记处和全球其他几个 COVID-19 登记处的经验。在试点阶段，纳入了 120 名儿童的便利样本，其中 66 名（55%）为男性。
来自其他 COVID-19 登记处的经验和专业知识；世界卫生组织提供的指导；以及在这些充满挑战的时期，利益相关者、研究小组和数据录入员之间的有效合作与协作，对于登记处的开发和实施至关重要。我们的结果与国际报告相似，表明大多数儿童表现为轻度疾病（69.2%），大多数（70.2%）的胸部 X 光正常，最常见的首发症状是发热（77%）。
我们预计 PCR-Q8 的发展将成为科威特儿童深入研究 SARS-CoV-2 感染的垫脚石，并为建立其他登记处奠定基础。
