超声造影在诊断直径小于2厘米的BI-RADS-US 4a类病变中的价值
The value of contrast-enhanced ultrasound in the diagnosis of BI-RADS-US 4a lesions less than 2 cm in diameter.
作者信息
Yu Mei-Qin, Zhang Li-Li, Jiang Li-Ping, Zhou Ai-Yun
机构信息
Department of Ultrasound Medicine, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
出版信息
Clin Hemorheol Microcirc. 2023;83(3):195-205. doi: 10.3233/CH-221460.
BACKGROUND
Breast cancer is the most common malignant tumor in women. Early diagnosis of benign and malignant breast tumors is of great significance.
OBJECTIVE
To retrospectively analyze the value of contrast-enhanced ultrasonography (CEUS) in the diagnosis of Breast Imaging-Reporting and Data System (BI-RADS) 4a breast lesions less than 2 cm in diameter.
METHODS
CEUS was performed for 143 breast masses less than 2 cm in diameter that were diagnosed as BI-RADS 4a by ultrasound and reclassified. Considering pathological diagnosis as the gold standard, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of reclassified lesions after CEUS for the diagnosis of benign and malignant masses were analyzed.
RESULTS
BI-RADS 4a breast masses with a diameter less than 2 cm (n = 143) were confirmed by pathology; 103 and 40 were classified as benign and malignant, respectively. The sensitivity, specificity, PPV, and NPV of CEUS for the diagnosis were 90%, 86%, 72%, and 95%, respectively. The area under the receiver operating characteristic (ROC) curve of CEUS for the diagnosis of benign and malignant tumors after CEUS was 0.904.
CONCLUSION
CEUS can help to improve the diagnostic accuracy of BI-RADS 4a masses with a diameter less than 2 cm.
背景
乳腺癌是女性最常见的恶性肿瘤。乳腺良恶性肿瘤的早期诊断具有重要意义。
目的
回顾性分析超声造影（CEUS）在诊断直径小于2 cm的乳腺影像报告和数据系统（BI-RADS）4a类乳腺病变中的价值。
方法
对143例直径小于2 cm、超声诊断为BI-RADS 4a类的乳腺肿块进行CEUS检查并重新分类。以病理诊断为金标准，分析CEUS检查后重新分类的病变对良恶性肿块诊断的灵敏度、特异度、阳性预测值（PPV）和阴性预测值（NPV）。
结果
143例直径小于2 cm的BI-RADS 4a类乳腺肿块经病理证实；分别有103例和40例被分类为良性和恶性。CEUS诊断的灵敏度、特异度、PPV和NPV分别为90%、86%、72%和95%。CEUS诊断良恶性肿瘤的受试者操作特征（ROC）曲线下面积为0.904。
结论
CEUS有助于提高直径小于2 cm的BI-RADS 4a类肿块的诊断准确性。
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