Department of Pediatrics, University of Western Ontario, Division of Neonatal-Perinatal Medicine, London, ON, Canada.
University of Alberta, Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Edmonton, Alberta, Canada.
J Neonatal Perinatal Med. 2022;15(4):689-697. doi: 10.3233/NPM-210943.
Optimal fluid management of preterm babies with suspected or confirmed diagnosis of patent ductus arteriosus (PDA) is frequently challenging for neonatal care physician because of paucity of clinical trials. There is wide variation in practice across neonatal units, resulting in significant impact on outcomes in Extremely Low Birth Weight (ELBW) babies with hemodynamically significant PDA. A delicate balance is required in fluid management to reduce mortality and morbidity in this population. The purpose of this review is to lay out the current understanding about fluid and electrolyte management in ELBW babies with hemodynamically significant PDA and highlight areas for future research.
对于新生儿科医生来说，患有或疑似患有动脉导管未闭（PDA）的早产儿的最佳液体管理常常具有挑战性，因为临床试验很少。新生儿病房的实践存在很大差异，这对患有中重度 PDA 的极低出生体重（ELBW）婴儿的结局产生了重大影响。在液体管理中需要达到微妙的平衡，以降低该人群的死亡率和发病率。本文旨在阐述目前对中重度 PDA 的 ELBW 婴儿的液体和电解质管理的认识，并强调未来的研究方向。
