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我们应该“消除”早产儿的动脉导管未闭分流吗?一篇叙述性综述。

Should we "eliminate" PDA shunt in preterm infants? A narrative review.

作者信息

Surak Aimann, Sidhu Amneet, Ting Joseph Y

机构信息

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, McMaster University, Hamilton, ON, Canada.

出版信息

Front Pediatr. 2024 Feb 6;12:1257694. doi: 10.3389/fped.2024.1257694. eCollection 2024.

Abstract

The patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In addition, treatment has not demonstrated definitive improvements in patient outcomes. Currently, the optimal approach remains a subject of considerable debate with ongoing research controversy regarding the best approach. This article provides a comprehensive review of existing literature.

摘要

动脉导管未闭在早产儿中常常会引发严重的发病情况,使其未成熟的肺血管床承受大量的容量负荷。这进而导致导管后器官同时出现灌注不足,随后改变脑血流量。此外,治疗并未在患者预后方面显示出明确的改善。目前,最佳治疗方法仍是一个备受争议的话题,关于最佳方法的研究仍存在争议。本文对现有文献进行了全面综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3eb6/10876852/9d68d1e3060d/fped-12-1257694-g001.jpg

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