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非尼拉敏诱发的对腺苷耐药的室上性心动过速:一例报告及文献复习

Pheniramine induced supraventricular tachycardia resistant to adenosine: A case report and review.

作者信息

Mohamud Mohamed Farah Yusuf, Waberi Mohamud Mire

机构信息

Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia.

出版信息

Ann Med Surg (Lond). 2022 Apr 20;78:103621. doi: 10.1016/j.amsu.2022.103621. eCollection 2022 Jun.

Abstract

Cardiac toxicity is a very seldom documented side effect of Pheniramine. Although second-generation antihistamines such as terfenadine and astemizole have been linked to cardiac injury, the incidence of SVT after Pheniramine treatment on adult clinical dose is currently unknown. In this case, we present a 22-year-old girl who developed adenosine-resistant supraventricular tachycardia (SVT) after being given pheniramine due to a bean allergy. It is crucial to know that symptomatic SVT could occur with therapeutic doses of pheniramine. This case highlights the importance of a comprehensive drug evaluation in emergency situations to identify the underlying etiologies and prompt treatment commencement. It also emphasizes the significance of assessing and choosing acute drugs for each patient admitted to the emergency unit to ensure the start of a newer medication if necessary.

摘要

心脏毒性是吩那敏一种很少被记录的副作用。虽然第二代抗组胺药如特非那定和阿司咪唑与心脏损伤有关,但目前尚不清楚成人临床剂量服用吩那敏后室上性心动过速(SVT)的发生率。在此病例中,我们报告一名22岁女孩,因豆类过敏服用吩那敏后出现对腺苷耐药的室上性心动过速(SVT)。必须知道,治疗剂量的吩那敏可能会引发有症状的室上性心动过速。该病例突出了在紧急情况下进行全面药物评估以确定潜在病因并迅速开始治疗的重要性。它还强调了对入住急诊科的每位患者评估和选择急性药物的重要性,以便在必要时确保开始使用更新的药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b11/9121280/2e5a20319bc9/gr1.jpg

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