Masatu Emmanuel S, Kajura Alphaxard, Mujuni Fridolin, Chibwe Elieza, Nyawale Helmut A, Rambau Peter, Majigo Mtebe, Mshana Stephen E, Mirambo Mariam M
Department of Obstetrics and Gynaecology, Weill Bugando School of Medicine, Catholic University of Health and Allied sciences, Mwanza, Tanzania.
Department of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
SAGE Open Med. 2022 May 17;10:20503121221097536. doi: 10.1177/20503121221097536. eCollection 2022.
Placement of intrauterine contraceptive device (IUCD) in asymptomatic woman infected with sexually transmitted infection (STIs) can lead to pelvic inflammatory diseases (PID) and infertility if not well treated. The current study investigated the magnitude of sexually transmitted infections among women opting for IUCD use in the city of Mwanza, Tanzania.
A cross-sectional study involving 150 asymptomatic women was conducted from August to December 2017. Detection of antigen from endocervical swabs was done using immunochromatographic rapid tests while sera were used for detection of , human immunodeficiency virus (HIV) and herpes simplex virus Type 2 (HSV-2) antibodies.
The overall prevalence of STIs was 45/150 (30%, 95% CI: 22-37) while that of individual STIs were 27.3%, 5.3%, and 2.6% for , , and HSV-2, respectively. History of dysuria (aOR 6.6; 95% CI 2.3-18.8; p < 0.001) and history of STIs (aOR 4.6; 95%CI 1.0-20.8; p = 0.049) independently predicted presence of STIs.
Prevalence of STIs among women opted for IUCD use in the city of Mwanza, Tanzania is alarmingly high and is predicted by past history of dysuria and history of partner's STIs, calling for the need of screening of the STIs among high-risk women in low- and middle-income countries (LMICs) opting for IUCD use.
对于感染性传播感染（STIs）的无症状女性，如果宫内节育器（IUCD）放置后未得到妥善治疗，可能会导致盆腔炎性疾病（PID）和不孕。本研究调查了坦桑尼亚姆万扎市选择使用IUCD的女性中性传播感染的感染程度。
2017年8月至12月进行了一项横断面研究，纳入150名无症状女性。使用免疫层析快速检测法检测宫颈拭子中的抗原，同时使用血清检测沙眼衣原体、人免疫缺陷病毒（HIV）和2型单纯疱疹病毒（HSV-2）抗体。
STIs的总体患病率为45/150（30%，95%CI：22 - 37），而沙眼衣原体、淋病奈瑟菌和HSV-2的个体患病率分别为27.3%、5.3%和2.6%。尿痛病史（调整后比值比[aOR] 6.6；95%CI 2.3 - 18.8；p < 0.001）和性传播感染病史（aOR 4.6；95%CI 1.0 - 20.8；p = 0.049）可独立预测性传播感染的存在。
在坦桑尼亚姆万扎市选择使用IUCD的女性中性传播感染的患病率高得惊人，且可通过既往尿痛病史和性伴侣的性传播感染病史预测，这表明在低收入和中等收入国家（LMICs）选择使用IUCD的高危女性中需要进行性传播感染筛查。
