Presley J J, Hernandez E, Mudafort E, Miyazawa K
J Reprod Med. 1987 Feb;32(2):99-102.
The medical records and histopathology of 250 patients who underwent cervical conization between January 1979 and December 1982 were reviewed. Two hundred thirty (92%) had endometrial curettage at the time of cervical conization. Abnormal findings were present in 7 (3%) of the 230 curettings. Limiting the performance of endometrial curettage at the time of conization to patients meeting specific criteria would have reduced the number of combined procedures by 75% without jeopardizing our ability to detect significant pathology. Endocervical curettage was performed on 221 (88%) of the 250 patients undergoing conization. The endocervical curettings were not a good predictor of the involvement of the cone margins with neoplasia. Only 7 (20%) of 35 patients with involved endocervical margins had a positive endocervical curettage. While the cone margins predicted residual carcinoma in the hysterectomy specimen with a sensitivity of 1.0, the sensitivity of the endocervical curettings for predicting residual carcinoma was 0.5. Although endocervical curettings can detect an invasive cancer not detected in the cone specimen, a negative endocervical curettage does not rule out invasive cancer above the excision line.
回顾了1979年1月至1982年12月期间接受宫颈锥切术的250例患者的病历和组织病理学情况。230例(92%)在宫颈锥切术时进行了子宫内膜刮除术。230次刮除术中7例(3%)有异常发现。将锥切术时子宫内膜刮除术的实施限于符合特定标准的患者,可使联合手术数量减少75%,而不影响我们检测重要病变的能力。250例接受锥切术的患者中有221例(88%)进行了宫颈管刮除术。宫颈管刮除术对锥切边缘是否存在肿瘤累及不是一个很好的预测指标。35例宫颈管边缘受累的患者中只有7例(20%)宫颈管刮除术结果为阳性。虽然锥切边缘对子宫切除标本中残留癌的预测敏感性为1.0,但宫颈管刮除术对预测残留癌的敏感性为0.5。虽然宫颈管刮除术可检测到锥切标本中未发现的浸润癌,但宫颈管刮除术结果为阴性并不能排除切除线上方存在浸润癌。