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用于放射学和形态测量学的人体肺部标准化固定;一种采用甲醛蒸汽充盈的“双腔”系统的描述

Standardized fixation of human lung for radiology and morphometry; Description of a "two chamber"-system with formaldehyde vapor inflation.

作者信息

Mittermayer C, Wybitul K, Rau W S, Ostendorf P, Riede U N

出版信息

Pathol Res Pract. 1978 May;162(1):115-30. doi: 10.1016/S0344-0338(78)80134-4.

Abstract

In order to obtain optimal preservation of lungs for histology, morphometry and radiology a two-chamber system of lung fixation with hot formaldehyde vapor is introduced. Compared with other procedures this system offers small dead space and ensures quick and thorough fixation by imitating "inspiration" and "expiration". Volume- and pressure-regulated "breathing" enables fixation in a stage of the respiration cycle, which can be chosen. This procedure can be used routinely in the autopsy room. The only serious drawback seems to be air pollution, if the chambers are not absolutely insulated.

摘要

为了实现对肺组织进行组织学、形态计量学和放射学的最佳保存,引入了一种用热甲醛蒸汽进行肺固定的双腔系统。与其他方法相比,该系统死腔小,通过模拟“吸气”和“呼气”确保快速、彻底的固定。体积和压力调节的“呼吸”能够在可选择的呼吸周期阶段进行固定。该方法可在尸检室常规使用。如果腔室没有完全隔热,唯一严重的缺点似乎是空气污染。

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