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4-羟基肉桂酸的无催化剂脱羧反应:4-乙烯基苯酚的高效合成

Catalyst-free decarboxylation of 4-hydroxycinnamic acids: efficient synthesis of 4-vinylphenols.

作者信息

Yang Qian, Li Youjuan, Liu Huanhuan, Wang Enhua, Peng Mei, Deng Tingfei, Pan Xiong, Luo Zhongsheng, Yan Yanfang, Yang Lishou, Yang Xiaosheng

机构信息

Department of Medicine and Food, Guizhou Vocational College of Agriculture, Guiyang 550041, People's Republic of China.

State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, People's Republic of China.

出版信息

R Soc Open Sci. 2022 Apr 27;9(4):220014. doi: 10.1098/rsos.220014. eCollection 2022 Apr.

Abstract

We report herein an efficient protocol for the synthesis of 4-vinylphenols by a catalyst-free decarboxylation of -4-hydroxycinnamic acids. A variety of 4-vinylphenols has been synthesized in moderate to excellent yields. This protocol also features no polymerization.

摘要

我们在此报告一种通过4-羟基肉桂酸的无催化剂脱羧反应合成4-乙烯基苯酚的有效方法。已以中等至优异的产率合成了多种4-乙烯基苯酚。该方法的特点还包括无聚合反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7649/9043707/b25f8c3a55c0/rsos220014f01.jpg

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