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切开手术期间口服异维甲酸（泰尔丝）：安全还是有风险？

Oral isotretinoin (Roaccutane) use during incisional surgery: safe or risky?

作者信息

Davies Matthew J, Perkins Darrell

机构信息

St George and Sutherland Clinical School, Faculty of Medicine, UNSW, Sydney, Australia.

Department of Plastic Surgery, St George Hospital, Kogarah, Australia.

出版信息

Case Reports Plast Surg Hand Surg. 2022 May 13;9(1):131-134. doi: 10.1080/23320885.2022.2071275. eCollection 2022.

DOI:10.1080/23320885.2022.2071275
PMID:35601983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9116253/
Abstract

Two cases are presented that demonstrate normal wound healing following bilateral reduction mammoplasty, in young female patients taking therapeutic doses of Isotretinoin (Roaccutane). Review of the literature does not provide evidence that Isotretinoin impairs would healing, nor that it promotes hypertrophic or keloid scarring in surgical patients.

摘要

本文介绍了两例在服用治疗剂量异维A酸（泰尔丝）的年轻女性患者中，双侧乳房缩小成形术后伤口正常愈合的病例。文献综述未提供证据表明异维A酸会损害伤口愈合，也未表明它会促进手术患者出现增生性或瘢痕疙瘩性瘢痕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2058/9116253/f1187013cc32/ICRP_A_2071275_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2058/9116253/bfd488e70a1f/ICRP_A_2071275_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2058/9116253/f1187013cc32/ICRP_A_2071275_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2058/9116253/bfd488e70a1f/ICRP_A_2071275_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2058/9116253/f1187013cc32/ICRP_A_2071275_F0002_C.jpg

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Oral isotretinoin (Roaccutane) use during incisional surgery: safe or risky?切开手术期间口服异维甲酸（泰尔丝）：安全还是有风险？
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JMIR Dermatol. 2023 Aug 10;6:e45351. doi: 10.2196/45351.
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JMIR Dermatol. 2023 Aug 10;6:e45351. doi: 10.2196/45351.

本文引用的文献

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Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations.异维 A 酸与手术干预时机：一项系统评价及共识推荐
JAMA Dermatol. 2017 Aug 1;153(8):802-809. doi: 10.1001/jamadermatol.2017.2077.
2
Surgical Outcome in Patients Taking Concomitant or Recent Intake of Oral Isotretinoin: A Multicentric Study-ISO-AIMS Study.正在服用或近期服用口服异维A酸患者的手术结局：一项多中心研究——ISO - AIMS研究
J Cutan Aesthet Surg. 2016 Apr-Jun;9(2):106-14. doi: 10.4103/0974-2077.184054.
3
Is It Safe to Operate on Patients Taking Isotretinoin?
给服用异维甲酸的患者做手术安全吗？
Aesthetic Plast Surg. 2016 Feb;40(1):139-48. doi: 10.1007/s00266-015-0588-3. Epub 2015 Dec 18.
4
Complete remission of recalcitrant genital warts with a combination approach of surgical debulking and oral isotretinoin in a patient with systemic lupus erythematosus.系统性红斑狼疮患者采用手术切除联合口服异维 A 酸治疗难治性生殖器疣达到完全缓解。
Dermatol Ther. 2014 Mar-Apr;27(2):79-82. doi: 10.1111/dth.12059. Epub 2013 May 21.
5
Should isotretinoin be stopped prior to surgery? A critically appraised topic.异维A酸在手术前是否应停用？一个严格评估的主题。
Br J Dermatol. 2014 Feb;170(2):239-44. doi: 10.1111/bjd.12761.
6
Lip abscess associated with isotretinoin treatment of acne vulgaris.唇痈与异维 A 酸治疗寻常痤疮相关。
JAMA Dermatol. 2013 Aug;149(8):960-1. doi: 10.1001/jamadermatol.2013.4066.
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Does systemic isotretinoin inhibit healing in a porcine wound model?全身性异维 A 酸是否会抑制猪模型伤口的愈合？
Aesthet Surg J. 2012 Nov;32(8):989-98. doi: 10.1177/1090820X12462383.
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The effects of isotretinoin on wisdom tooth extraction.异维A酸对智齿拔除的影响。
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Complications associated with isotretinoin use after rhinoplasty.隆鼻术后使用异维A酸相关的并发症。
Aesthetic Plast Surg. 2005 Mar-Apr;29(2):102-6. doi: 10.1007/s00266-004-0041-5. Epub 2005 Apr 7.
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