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七氟烷吸入及麻醉诱导对择期胃肠道肿瘤手术老年患者血流动力学的影响

Effect of Heptaflourane Inhalation and Anesthesia Induction on Hemodynamics of Elderly Patients Undergoing Elective Gastrointestinal Tumor Surgery.

作者信息

Ren Guozhang, Li Chen, Wei Xiaoxia, Wang Jing

机构信息

Department of Anesthesiology, Yantai Hospital of Traditional Chinese Medicine, Yantai, 264000 Shandong, China.

Department of Anesthesiology, Jinan Second People's Hospital, Jinan, 250001 Shandong, China.

出版信息

J Oncol. 2022 May 13;2022:9022614. doi: 10.1155/2022/9022614. eCollection 2022.

Abstract

Gastrointestinal stromal tumors (GISTs) are rare malignancies that begin in specific cells in the GI tract's (also known as the digestive tract's) wall. The microenvironment of gastrointestinal cancers has gotten a lot of interest in the last decade. There are various obstacles connected with providing care to individuals with gastrointestinal cancers, especially the elderly. The physiological reserves of elderly individuals are generally depleted, and comorbidities might limit treatment options and increase problems. Surgeons and anesthesiologists must be aware of the measures that must be used while dealing with this fragile population. Anesthesia is a term that refers to the use of drugs to alleviate pain during the surgery and other treatments. Anesthesia is crucial to a patient's successful treatment and recovery. To induce and maintain general anesthesia in the operating room, inhalation anesthetics (isoflurane, halothane, nitrous oxide, sevoflurane, and desflurane, the most commonly used agents in practice today) are utilized. Inhalation anesthetics are drugs used to give general anesthesia for surgery in the operating room. Anesthetics have the potential to cause substantial cardiac depression as well as hemodynamic instability. In this study, we propose the SBWOA (spark bumper whale optimization algorithm), which is used to assess the patient's risk before surgery. The entire experiment was run through Matlab simulations.

摘要

胃肠道间质瘤(GISTs)是一种罕见的恶性肿瘤,起源于胃肠道(也称为消化道)壁中的特定细胞。在过去十年中,胃肠道癌症的微环境受到了广泛关注。为胃肠道癌症患者提供护理存在各种障碍,尤其是对于老年人。老年人的生理储备通常会耗尽,合并症可能会限制治疗选择并增加问题。外科医生和麻醉师必须了解在处理这一脆弱人群时必须采取的措施。麻醉是指在手术和其他治疗过程中使用药物减轻疼痛。麻醉对于患者的成功治疗和康复至关重要。在手术室中,为了诱导和维持全身麻醉,会使用吸入麻醉剂(异氟烷、氟烷、氧化亚氮、七氟烷和地氟烷,这些是当今实践中最常用的药物)。吸入麻醉剂是用于在手术室中进行手术全身麻醉的药物。麻醉剂有可能导致严重的心脏抑制以及血流动力学不稳定。在本研究中,我们提出了火花碰撞鲸鱼优化算法(SBWOA),该算法用于在手术前评估患者的风险。整个实验通过Matlab模拟运行。

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