Brikho Salam, Zughaib Marc T, Tsaloff Grace, Smythe Ken, Zughaib Marcel E
Internal Medicine, Ascension Providence Hospital, Southfield, USA.
Internal Medicine, Michigan State University College of Human Medicine, Lansing, USA.
Cureus. 2022 Apr 19;14(4):e24292. doi: 10.7759/cureus.24292. eCollection 2022 Apr.
Pulmonary embolism (PE) is a diagnosis on the broader spectrum of venous thromboembolic (VTE) disease. The diagnostic key for clinicians is detecting which patients have a "high risk" of complications or mortality and who are in the "low-risk" population. The Pulmonary Embolism Severity Index (PESI) and HESTIA scores are validated risk stratification tools to determine if patients diagnosed with PE can be successfully managed in the outpatient versus inpatient setting. We aimed to investigate the appropriateness of PE admissions to our institution based on the risk stratification recommendations from PESI and HESTIA scores. We retrospectively identified 175 patients admitted with a diagnosis of PE over one year at our hospital. Baseline demographics, length of admission, and admitting diagnoses were collected for all patients included in this study. PESI and HESTIA scores were then calculated for all included patients. The average PESI score was 91.65 (95% confidence interval: 86.33, 96.97). There were 87 patients (49.7%) that had a low or very low PESI score of fewer than 85 points. Fifty-seven patients (33.7%) presented with a HESTIA score of 0. The risk stratification score indicates these patients as low risk, and appropriate for outpatient management. However, they were instead admitted to the hospital which contributes to increased costs, risk of adverse events, etc. There were 0 mortalities reported for patients in the "low or very low risk" groups, with four reported mortalities in the "very high risk" groups. In our cohort, 33.7%-49.7% of admissions for PE were risk-stratified as "low risk" and qualified for outpatient management based on HESTIA and PESI risk stratification scores, respectively. The underutilization of validated risk scores upon initial diagnosis of PE may lead to worse outcomes and increased healthcare expenditure.
肺栓塞(PE)是更广泛的静脉血栓栓塞性(VTE)疾病谱中的一种诊断。临床医生的诊断关键在于识别哪些患者有并发症或死亡的“高风险”,以及哪些患者属于“低风险”人群。肺栓塞严重程度指数(PESI)和HESTIA评分是经过验证的风险分层工具,用于确定诊断为PE的患者是否可以在门诊或住院环境中成功管理。我们旨在根据PESI和HESTIA评分的风险分层建议,调查我院PE住院治疗的适宜性。我们回顾性地确定了我院在一年时间内收治的175例诊断为PE的患者。收集了本研究中所有患者的基线人口统计学数据、住院时间和入院诊断。然后为所有纳入患者计算PESI和HESTIA评分。平均PESI评分为91.65(95%置信区间:86.33,96.97)。有87例患者(49.7%)的PESI评分为低或极低,低于85分。57例患者(33.7%)的HESTIA评分为0。风险分层评分表明这些患者为低风险,适合门诊管理。然而,他们却被收治入院,这导致了成本增加、不良事件风险增加等问题。“低或极低风险”组的患者报告无死亡病例,“极高风险”组报告有4例死亡病例。在我们的队列中,分别根据HESTIA和PESI风险分层评分,33.7%-49.7%的PE入院患者被风险分层为“低风险”,有资格进行门诊管理。PE初诊时未充分利用经过验证的风险评分可能会导致更差的结果和医疗费用增加。