2nd Cardiology Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
2nd Cardiology Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Hellenic J Cardiol. 2022 Sep-Oct;67:28-35. doi: 10.1016/j.hjc.2022.05.007. Epub 2022 May 21.
Fagerstrom score is a validated marker of nicotine addiction in smokers.
In a prospective study, we investigated a) the predictive value of Fagerstrom score for the smoking status in patients early after acute myocardial infarction (AMI) and b) the effectiveness of medically assisted smoking cessation programs in the prevention of relapsing to smoking post discharge. In 103 smokers (58 ± 12 years, 79.6% males), we assessed Fagerstrom score during hospitalization for AMI. Patients filled a dedicated questionnaire including data on family, marital and educational status, habits related to smoking and were followed-up at 3 and 6 months after discharge.
Twenty-eight patients (27.2%) did not quit smoking throughout the 6-months follow-up period (Fagerstrom score:8.1 ± 1.6), 39 patients (37.8%) ceased smoking at 3 months but relapsed to smoking at 6 months (score:6.8 ± 2.1), and only 34 patients (33%) had ceased smoking for 6 consecutive months (score:5.2 ± 2 p < 0.05 for all comparisons between subgroups). By multivariate analysis, Fagerstrom score remained a significant predictor of smoking cessation at 6 months (OR: 0.72, 95%CI: 0.60--0.86, p < 0.001). Out of 73 patients who abstained from smoking for the first 3 months post-AMI, those who participated in a smoking cessation program displayed lower rate of relapsing to smoking compared with those who opted to cease smoking without any support (33.3% vs 61.8% p = 0.012).
Fagerstrom score is a useful predictor of smoking cessation 6 months post-AMI. Patients participating in a smoking cessation program display lower relapse rates post-discharge suggesting the need of well-organized smoking cessation clinics for secondary prevention of heart disease.
Fagerstrom 评分是吸烟者尼古丁成瘾的有效标志物。
在一项前瞻性研究中，我们调查了 a）Fagerstrom 评分在急性心肌梗死（AMI）后早期患者吸烟状况中的预测价值，以及 b）医疗辅助戒烟方案在预防出院后复吸吸烟的有效性。在 103 名吸烟者（58±12 岁，79.6%为男性）中，我们在 AMI 住院期间评估了 Fagerstrom 评分。患者填写了一份专门的问卷，其中包括有关家庭、婚姻和教育状况、与吸烟有关的习惯的数据，并在出院后 3 个月和 6 个月进行随访。
28 名患者（27.2%）在 6 个月的随访期间未戒烟（Fagerstrom 评分：8.1±1.6），39 名患者（37.8%）在 3 个月时戒烟，但在 6 个月时复吸（评分：6.8±2.1），只有 34 名患者（33%）连续 6 个月戒烟（评分：5.2±2 p<0.05 所有亚组之间的比较）。多变量分析显示，Fagerstrom 评分仍然是 6 个月时戒烟的显著预测因子（OR：0.72，95%CI：0.60--0.86，p<0.001）。在 73 名 AMI 后前 3 个月戒烟的患者中，参加戒烟计划的患者与选择不支持戒烟的患者相比，复吸吸烟的比例较低（33.3%vs61.8%p=0.012）。
Fagerstrom 评分是 AMI 后 6 个月戒烟的有效预测因子。参加戒烟计划的患者出院后复发率较低，这表明需要有组织良好的戒烟诊所来进行心脏病的二级预防。
