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[儿童和成人动脉粥样硬化前驱病变的流行病学及预防研究]

[Epidemiologic and preventive studies of the precursors of atherosclerosis in children and adults].

作者信息

Aleksandrov A A, Isakova G L, Shamarin V M, Shugaeva E N, Maslennikova G L

出版信息

Kardiologiia. 1987 Jan;27(1):46-50.

PMID:3560627
Abstract

A total of 1920 schoolchildren of both sexes were examined at 12 to 13 years of age, with a follow-up of 242 children showing elevated BP and a random normotensive sample of 230. A set of features was identified that showed the greatest predictive value with respect to mean BP at five years' follow-up: baseline BP, the Katle index, the magnitude of the S wave and heart rate. A study of possible approaches to the prevention of atherosclerotic precursors in eleven-year-olds has been launched, with the action on certain risk factors, such as limited physical activity, elevated BP, smoking, excessive body weight lipid disorders (in boys only).

摘要

共有1920名12至13岁的男女学童接受了检查,对242名血压升高的儿童进行了随访,并随机抽取了230名血压正常的儿童作为样本。确定了一组特征,这些特征在五年随访中对平均血压显示出最大的预测价值:基线血压、卡特指数、S波幅度和心率。已经开展了一项针对11岁儿童预防动脉粥样硬化先兆的可能方法的研究,针对某些风险因素采取行动,如体育活动受限、血压升高、吸烟、体重超标、脂质紊乱(仅针对男孩)。

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