KSNM60：韩国放射性药物科学史
KSNM60: The History of Radiopharmaceutical Sciences in Korea.
作者信息
Yoo Ran Ji, Lee Yun-Sang, Lee Kyo Chul, Kim Dong Wook, Kim Dong-Yeon, Choe Yearn Seong, Jeong Jae Min
机构信息
Department of Nuclear Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080 Republic of Korea.
Division of Applied RI, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea.
出版信息
Nucl Med Mol Imaging. 2022 Jun;56(3):114-126. doi: 10.1007/s13139-022-00744-8. Epub 2022 Apr 5.
Abstract
A number of researchers in Korea have tried to set-up the production of radionuclides and develop new radiopharmaceuticals for several decades. Thanks to their 60-year endeavor to advance the field of radiopharmaceutical sciences, now we have a lot of research units and facilities in Korea. Still, there are huge number of issues to be solved in radiopharmaceutical sciences; however, our efforts will be continued to develop new radiopharmaceuticals and to apply the new radiopharmaceuticals into nuclear medicine field.
摘要
几十年来，许多韩国研究人员一直试图建立放射性核素的生产体系并开发新的放射性药物。经过他们在放射性药物科学领域60年的努力，如今韩国拥有众多研究单位和设施。尽管如此，放射性药物科学仍有大量问题有待解决；不过，我们将继续努力开发新的放射性药物，并将这些新的放射性药物应用于核医学领域。
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2
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Bioorg Med Chem. 2020 Jan 1;28(1):115212. doi: 10.1016/j.bmc.2019.115212. Epub 2019 Nov 9.
3
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J Nucl Med. 2019 Jul;60(7):924-929. doi: 10.2967/jnumed.118.221416. Epub 2018 Dec 14.
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Naphthol Blue Black and Tc-Labeled Mannosylated Human Serum Albumin (Tc-MSA) Conjugate as a Multimodal Lymph Node Mapping Nanocarrier.萘酚蓝黑和 Tc 标记的甘露糖化人血清白蛋白（Tc-MSA）缀合物作为一种多模式淋巴结示踪纳米载体。
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J Cereb Blood Flow Metab. 2017 Jun;37(6):2283-2293. doi: 10.1177/0271678X16663948. Epub 2016 Jan 1.
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