Frankel B L, Patel D J, Horwitz D, Friedewald W T, Gaarder K R
Psychosom Med. 1978 Jun;40(4):276-93. doi: 10.1097/00006842-197806000-00002.
The present study describes a 16-week trial of the use of a combination of biofeedback and relaxation techniques for the treatment of hypertension. Twenty-two hypertensive patients were randomly allocated to one of three groups: (1) diastolic blood pressure feedback, electromyographic feedback, and verbal relaxation; (2) sham blood pressure feedback; and (3) no treatment. For the 14 patients completing active treatment during an initial or crossover period, the average changes in blood pressure as measured outside the laboratory were minimal (0/-1 and +1/0 mm Hg, supine and standing, respectively). Average blood pressure reduction in the laboratory was no greater with active than with sham blood pressure feedback (-3/-2 vs. -5/-2 mm Hg). One subject, however, after showing no change in blood pressure during sham feedback, achieved pronounced and prolonged improvement following active treatment. Overall results do not support the usefulness of these techniques as primary therapy in most hypertensives.
本研究描述了一项为期16周的试验，该试验使用生物反馈和放松技术相结合的方法来治疗高血压。22名高血压患者被随机分配到三组中的一组：（1）舒张压反馈、肌电图反馈和言语放松；（2）假血压反馈；（3）不治疗。对于在初始或交叉期完成积极治疗的14名患者，实验室外测量的血压平均变化极小（仰卧位和站立位分别为0/-1和+1/0毫米汞柱）。在实验室中，积极治疗组的平均血压降低幅度并不比假血压反馈组更大（-3/-2与-5/-2毫米汞柱）。然而，有一名受试者在假反馈期间血压没有变化，但在接受积极治疗后取得了显著且持久的改善。总体结果不支持这些技术在大多数高血压患者中作为主要治疗方法的有效性。
