Department of Pharmaceutical Chemistry, School of Pharmacy, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan-Aman, Ethiopia.
School of Pharmacy, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan-Aman, Ethiopia.
PLoS One. 2022 May 24;17(5):e0268971. doi: 10.1371/journal.pone.0268971. eCollection 2022.
Patient's knowledge about dispensed medications is one of the major factors that determine the rational use of medicines.
This study aimed to assess exit-knowledge of ambulatory patients about their dispensed medications and associated factors at the outpatient pharmacy of Mizan-Tepi University Teaching Hospital, Southwest Ethiopia.
A hospital-based cross-sectional study design was conducted from August to October 2021. Study subjects were selected by random sampling technique and were interviewed using a structured interview questionnaire. Binary logistic regression was used to identify factors associated with exit knowledge. At a 95% confidence interval (CI), p≤0.05 was considered statistically significant.
Of the total 400 participants, 116 (29.0%) participants had sufficient exit-knowledge about their dispensed medication. Patients with higher educational level had increased exit knowledge of dispensed medications than those with no formal education (AOR: 5.590; 95% CI 1.019-30.666). Also, the nature of illness as being chronic significantly enlarged the odds (AOR 5.807; 95% CI 2.965-11.372) of having sufficient exit-knowledge. Participants who reported, "I do not know" and "I did not get enough information from the pharmacist" had lower odds (AOR 0.374; 95% CI: 0.142-0.982) and (AOR 0.166; 95% CI 0.062-0.445) of sufficient exit-knowledge in comparison to those who responded "I got enough information from the pharmacist" respectively. Furthermore, the odd of sufficient exit-knowledge was 7.62 times higher in those who claimed prescribing doctor as the source of information.
The majority of patients had insufficient exit-knowledge about their dispensed medications. Educational status, nature of the disease, perceived sufficiency of pharmacist knowledge, and source of information were significantly associated with exit knowledge.
患者对所配药物的了解是决定药物合理使用的主要因素之一。
本研究旨在评估埃塞俄比亚西南部米赞-提皮大学教学医院门诊药房出院患者对所配药物的了解程度及其相关因素。
本研究采用 2021 年 8 月至 10 月期间进行的基于医院的横断面研究设计。采用随机抽样技术选择研究对象，并使用结构化访谈问卷对其进行访谈。采用二项逻辑回归来确定与出院知识相关的因素。置信区间为 95%（CI），p≤0.05 被认为具有统计学意义。
在总共 400 名参与者中，有 116 名（29.0%）参与者对其配药有足够的出院知识。文化程度较高的患者对所配药物的出院知识比没有正规教育的患者有所增加（AOR：5.590；95%CI 1.019-30.666）。此外，慢性病的性质显著增加了获得足够出院知识的几率（AOR 5.807；95%CI 2.965-11.372）。报告“我不知道”和“我从药剂师那里没有获得足够的信息”的参与者获得足够出院知识的几率较低（AOR 0.374；95%CI：0.142-0.982）和（AOR 0.166；95%CI 0.062-0.445）与那些回答“我从药剂师那里获得了足够的信息”的参与者相比。此外，声称医生为信息来源的患者获得足够出院知识的几率高 7.62 倍。
大多数患者对所配药物的出院知识了解不足。教育程度、疾病性质、对药剂师知识的感知充足程度以及信息来源与出院知识显著相关。
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