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在低收入国家,社区药房就诊患者的药物知识水平较低,对口服慢性病药物的依从性也较低:一项横断面研究。

Low Medication Knowledge and Adherence to Oral Chronic Medications among Patients Attending Community Pharmacies: A Cross-Sectional Study in a Low-Income Country.

机构信息

Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

Biomed Res Int. 2020 Jan 11;2020:4392058. doi: 10.1155/2020/4392058. eCollection 2020.

Abstract

OBJECTIVE

To investigate the level of knowledge, medication adherence, and the relationship among patients taking chronic oral medication and attending community pharmacies in Gondar, Northwest Ethiopia.

METHODS

A cross-sectional study was conducted among adult chronic disease patients who were taking oral medications and getting service in 19 community pharmacies in Gondar City, Northwest Ethiopia. Patients' medication knowledge and adherence were assessed using interviewer-administered validated questionnaires.

RESULTS

Of the 402 study participants (mean ± SD age = 44.7 ± 16.9 years, range = 18-86 years), 53.2% were males, 84.8% were aged <65 years, and 60.7% had high school education and above. About 348 (88.6%) respondents have used oral medications for more than one year. Less than half of respondents have good medication knowledge ( = 54, 38.3%) and were adherent to their medication ( = 158, 39.3%). Chronic disease patients with high school and above education are 5.35 times (95% CI: 3.231-8.857, < 0.001) more likely to have good knowledge of their medication and having good medication knowledge was linked to higher medication adherence (AOR, 95% CI = 10.300 [6.16517.209]; < 0.001). A statistically significant correlation was observed between the scores of medication knowledge and adherence ( = -0.471, < 0.001).

CONCLUSION

The majority of patients on oral chronic medications and attending community pharmacies in Gondar town do not have good medication knowledge and were nonadherent. Community pharmacists need to engage in medication counseling to improve medication knowledge and adherence of chronic disease patients.

摘要

目的

调查在埃塞俄比亚西北部贡德尔市服用慢性口服药物并在社区药房就诊的患者的知识水平、用药依从性以及三者之间的关系。

方法

本横断面研究纳入了在贡德尔市 19 家社区药房接受服务的正在服用口服药物的成年慢性病患者。使用经过验证的访谈式调查问卷评估患者的药物知识和用药依从性。

结果

在 402 名研究参与者(平均年龄±标准差为 44.7±16.9 岁,范围为 18-86 岁)中,53.2%为男性,84.8%年龄<65 岁,60.7%受过高中及以上教育。约 348 名(88.6%)患者使用口服药物的时间超过一年。不到一半的患者具有良好的药物知识(=54,38.3%)和用药依从性(=158,39.3%)。受过高中及以上教育的慢性病患者有良好药物知识的可能性是其他人的 5.35 倍(95%CI:3.231-8.857,<0.001),具有良好药物知识与较高的用药依从性相关(优势比,95%CI=10.300 [6.16517.209];<0.001)。药物知识和用药依从性评分之间存在显著的相关性(= -0.471,<0.001)。

结论

在贡德尔镇,大多数服用口服慢性药物并在社区药房就诊的患者没有良好的药物知识,且依从性差。社区药剂师需要开展药物咨询,以提高慢性病患者的药物知识和用药依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30e/7201603/ec3eacbd75c9/BMRI2020-4392058.001.jpg

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