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婴儿重症主动脉瓣狭窄的经心室主动脉瓣切开术

Transventricular aortic valvotomy for critical aortic stenosis in infants.

作者信息

Duncan K, Sullivan I, Robinson P, Horvath P, de Leval M, Stark J

出版信息

J Thorac Cardiovasc Surg. 1987 Apr;93(4):546-50.

PMID:3561001
Abstract

Ten infants with critical aortic stenosis underwent transventricular valvotomy between November 1983 and September 1984. The ages of the patients ranged from 1 to 38 days (mean 21.2 days). Three patients were less than 1 week of age. One had undergone a previous valvotomy performed with inflow occlusion. Most infants were critically ill when admitted to the hospital, six required inotropic and ventilatory support, and two had peritoneal dialysis before the operation. Transventricular valvotomy was performed through a left thoracotomy with Hegar dilators. Postvalvotomy peak-to-peak gradients ranged from 0 to 35 mm Hg. Three patients died at 2, 3, and 6 weeks after operation. A severe degree of endocardial fibroelastosis was present in one patient, and a second patient died of septicemia caused by wound infection, empyema, and a bronchopleural fistula. Severe left ventricular hypertrophy, with moderate fibroelastosis, was found at autopsy in the third patient. Aortic incompetence was not detected postoperatively. One patient required reoperation 7 months after the transventricular valvotomy. Transventricular valvotomy has proved to be a simple and effective technique to relieve aortic stenosis in sick infants. It permits the correction of associated coarctation of the aorta and avoids a median sternotomy. Results are comparable with the results obtained with either cardiopulmonary bypass or inflow occlusion as seen in both our experience and in the experience of others.

摘要

1983年11月至1984年9月期间,10例患有严重主动脉瓣狭窄的婴儿接受了经心室瓣膜切开术。患者年龄在1至38天之间(平均21.2天)。3例患者年龄小于1周。1例患者此前接受过流入道阻断下的瓣膜切开术。大多数婴儿入院时病情危重,6例需要使用正性肌力药物和通气支持,2例在手术前进行了腹膜透析。经心室瓣膜切开术通过左胸廓切开术使用黑加扩张器进行。瓣膜切开术后峰峰值压差为0至35毫米汞柱。3例患者分别在术后2周、3周和6周死亡。1例患者存在严重的心内膜弹力纤维增生症,另1例患者死于伤口感染、脓胸和支气管胸膜瘘引起的败血症。第3例患者尸检发现严重的左心室肥厚伴中度弹力纤维增生症。术后未检测到主动脉瓣关闭不全。1例患者在经心室瓣膜切开术后7个月需要再次手术。经心室瓣膜切开术已被证明是一种简单有效的技术,可缓解患病婴儿的主动脉瓣狭窄。它允许纠正相关的主动脉缩窄,避免正中胸骨切开术。我们的经验和其他人的经验均显示,其结果与体外循环或流入道阻断所获得的结果相当。

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