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欧洲前驱糖尿病和 2 型糖尿病的社会人口统计学、人体测量学和生活方式相关因素:Feel4Diabetes 研究。

Sociodemographic, anthropometric, and lifestyle correlates of prediabetes and type 2 diabetes in europe: The Feel4Diabetes study.

机构信息

Department of Nutrition and Dietetics, Harokopio University, 70 El Venizelou Avenue, Kallithea, Athens, 17671, Greece.

Laboratory of Dietetics and Quality of Life, Department of Food Science & Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, 75 Iera Odos, Athens, 11855, Greece.

出版信息

Nutr Metab Cardiovasc Dis. 2022 Aug;32(8):1851-1862. doi: 10.1016/j.numecd.2022.03.021. Epub 2022 Apr 2.

Abstract

BACKGROUND AND AIMS

The current work aimed to identify the predominant correlates of prediabetes and T2DM among a variety of socio-demographic, anthropometric and lifestyle indices, in a large sample of adults from families at high risk for T2DM.

METHODS AND RESULTS

In this cross-sectional study, 2816 adults were recruited from low-socioeconomic areas in high-income countries (HICs) (Belgium-Finland), HICs under austerity measures (Greece-Spain), and low/middle-income countries (LMICs) (Bulgaria-Hungary). A positive association between the male sex (OR, 95% C.I.2.77 (1.69-4.54)) and prediabetes was revealed compared to females, while there was a negative association between younger age (<45 years) (OR, 95% C.I. 0.58 (0.37-0.92)), and low/medium levels of waist circumference (OR, 95% C.I. 0.44 (0.22-0.89)) with prediabetes compared to older age and high levels of waist circumference, respectively. Concerning T2DM, 0-0.5 cups/day of fruits and berries (OR, 95% C.I.2. 13 (1.16-3.91)) and 150-300 g fish/week (OR, 95% C.I. 2.55 (1.01-6.41)) have a positive association compared to higher consumptions, respectively. Conversely, <1 cup/week legumes (OR, 95% C.I. 0.55 (0.31-0.99) as well as 0-0.5 servings (OR, 95% C.I. 0.34 (0.12-0.95) and 0.5-1 servings (OR, 95% C.I. 0.37 (0.19-0.71) of full-fat dairy/day have a negative association compared to higher consumptions, respectively.

CONCLUSION

These findings indicate the need for diabetes prevention measures targeting young adults and especially men, above 45 years of age, with central obesity and poor dietary habits and prioritize vulnerable groups and populations living in LMICs.

NATIONAL CLINICAL TRIAL NUMBER

NCT02393872.

摘要

背景与目的

本研究旨在确定在高收入国家(HICs)(比利时-芬兰)、面临财政紧缩措施的 HICs(希腊-西班牙)和中低收入国家(LMICs)(保加利亚-匈牙利)中,一系列社会人口学、人体测量学和生活方式指标中,哪些因素与糖尿病前期和 2 型糖尿病(T2DM)关系最密切。

方法和结果

在这项横断面研究中,共招募了来自高收入国家(HICs)(比利时-芬兰)、面临财政紧缩措施的 HICs(希腊-西班牙)和中低收入国家(LMICs)(保加利亚-匈牙利)的 2816 名成年人。与女性相比,男性(比值比[OR],95%置信区间[CI]2.77(1.69-4.54))与糖尿病前期呈正相关,而与女性相比,年轻(<45 岁)(OR,95%CI 0.58(0.37-0.92))和低/中等腰围(OR,95%CI 0.44(0.22-0.89))与糖尿病前期呈负相关。至于 T2DM,与较高摄入量相比,水果和浆果 0-0.5 杯/天(OR,95%CI 2.13(1.16-3.91))和每周 150-300 克鱼(OR,95%CI 2.55(1.01-6.41))与 T2DM 呈正相关。相反,与较高摄入量相比,每周食用<1 杯豆类(OR,95%CI 0.55(0.31-0.99))以及每周食用 0-0.5 份(OR,95%CI 0.34(0.12-0.95))和 0.5-1 份(OR,95%CI 0.37(0.19-0.71))全脂乳制品与 T2DM 呈负相关。

结论

这些发现表明,需要针对年轻成年人,特别是年龄超过 45 岁的男性,以及存在中心性肥胖和不良饮食习惯的人群,采取糖尿病预防措施,并优先考虑生活在 LMICs 的弱势群体和人群。

国家临床试验编号

NCT02393872。

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