Sander A K, Dietrich L, Kloss-Brandstätter A, Krause M, Zimmerer R, Neuhaus M, Bartella A K, Lethaus B
Department of Oral- and Maxillofacial Surgery, University Hospital Leipzig, Liebigstr. 12, 04103 Leipzig, Germany.
Department of Oral- and Maxillofacial Surgery, University Hospital Leipzig, Liebigstr. 12, 04103 Leipzig, Germany.
J Plast Reconstr Aesthet Surg. 2022 Sep;75(9):3429-3435. doi: 10.1016/j.bjps.2022.04.040. Epub 2022 Apr 27.
The objective of this study is to develop and validate a specific screening instrument for assessing the quality of life (QoL) of patients with orofacial clefts. The Cleft-Screen-Questionnaire (CSQ) aims at identifying the main problematic areas and is intended for the routine use in everyday clinical practice to constantly evaluate the conditions' and treatments' effects on patients' well-being.
First, a pool of 58 questions is created by collecting items from validated questionnaires previously used for assessing the QoL in cleft populations. After the removal of duplicate questions, the questionnaires are answered by 152 patients from a tertiary care center. A factor analysis followed by the calculation of Cronbach's alpha as a reliability measurement led to the final CSQ presented here.
The applied factor analysis resulted in five factors. Items showing low factor loadings (seen as <0.5) were excluded initially. Accordingly, factor analysis led to a preliminary number of 43 items. A reliability analysis using Cronbach's alpha and corrected alpha if item deleted showed an overall moderate to high reliability (seen as: 0.6-0.9). After excluding questions with increasing alphas if item deleted, analyses yielded in a final number of 38 questions.
The final 38-item CSQ is a reliable instrument for evaluating the health-related QoL of cleft patients.
本研究的目的是开发并验证一种用于评估口腔颌面部裂隙患者生活质量（QoL）的特定筛查工具。腭裂筛查问卷（CSQ）旨在识别主要问题领域，旨在在日常临床实践中常规使用，以持续评估病情和治疗对患者幸福感的影响。
首先，通过从先前用于评估腭裂人群生活质量的有效问卷中收集项目，创建了一个包含58个问题的题库。在去除重复问题后，来自三级护理中心的152名患者回答了这些问卷。进行因子分析，随后计算Cronbach's alpha作为可靠性度量，得出了此处展示的最终CSQ。
应用的因子分析产生了五个因子。最初排除了因子载荷较低（视为<0.5）的项目。因此，因子分析得出初步的43个项目。使用Cronbach's alpha以及删除项目后的校正alpha进行的可靠性分析显示出总体中等至高可靠性（视为：0.6 - 0.9）。在排除删除项目后alpha值增加的问题后，分析得出最终的38个问题。
最终的38项CSQ是评估腭裂患者健康相关生活质量的可靠工具。
