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表现为双侧上睑下垂和单侧内侧纵束综合征的旁正中脑梗死:一种特殊的中脑综合征

Paramedian Midbrain Infarction Presenting with Bilateral Ptosis and Unilateral Median Longitudinal Fasciculus Syndrome: A Peculiar Midbrain Syndrome.

作者信息

Aoki Yoshihiro, Hashimoto Takao

机构信息

Department of Emergency and Critical Care Medicine, Aizawa Hospital, Matsumoto, Japan.

Department of Neurology, Aizawa Hospital, Matsumoto, Japan.

出版信息

Case Rep Neurol. 2022 Apr 4;14(1):197-201. doi: 10.1159/000523986. eCollection 2022 Jan-Apr.

DOI:10.1159/000523986
PMID:35611360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9082153/
Abstract

We report a case of bilateral ptosis due to paramedian midbrain infarction, which was associated with ipsilateral impaired adduction of the eye and contralateral ataxia. T2-weighted magnetic resonance imaging of the brain revealed a right paramedian midbrain infarction. The ptosis rapidly improved without a difference between the left and right sides, while the other symptoms mostly resolved within a month following treatment with antiplatelet agents and rehabilitation. An infarction of the paramedian dorsocaudal portion of the midbrain can involve both the central caudal nucleus and the median longitudinal fasciculus (MLF), causing a peculiar combination of symptoms, bilateral ptosis, and unilateral MLF syndrome.

摘要

我们报告一例因中脑旁正中梗死导致的双侧上睑下垂病例,该病例伴有同侧眼球内收障碍和对侧共济失调。脑部T2加权磁共振成像显示右侧中脑旁正中梗死。上睑下垂迅速改善,左右两侧无差异,而其他症状在使用抗血小板药物和康复治疗后一个月内大多得到缓解。中脑背尾侧旁正中部分梗死可累及中央尾状核和内侧纵束(MLF),导致双侧上睑下垂和单侧MLF综合征等特殊症状组合。

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Brainstem stroke presenting as isolated bilateral ptosis.以孤立性双侧上睑下垂为表现的脑干卒中。
BMJ Case Rep. 2021 Jul 12;14(7):e243220. doi: 10.1136/bcr-2021-243220.
2
An Anatomic, Imaging, and Clinical Review of the Medial Longitudinal Fasciculus.内侧纵束的解剖学、影像学及临床综述
J Clin Imaging Sci. 2020 Dec 18;10:83. doi: 10.25259/JCIS_49_2020. eCollection 2020.
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Isolated and Transient Nuclear Midbrain Blepharoptosis in a Young and Healthy Adult.一名年轻健康成年人的孤立性短暂性核性中脑上睑下垂
Neuroophthalmology. 2019 Mar 22;44(2):111-113. doi: 10.1080/01658107.2019.1588336. eCollection 2020 Apr.
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Management of severe bilateral ptosis in a patient with midbrain infarction: a case report.中脑梗死患者严重双侧上睑下垂的管理:一例报告
Ann Rehabil Med. 2013 Dec;37(6):891-5. doi: 10.5535/arm.2013.37.6.891. Epub 2013 Dec 23.
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A case of midbrain infarction causing ipsilateral mydriasis, contralateral superior rectus palsy, and bilateral ptosis.
Neurol Sci. 2013 Sep;34(9):1683-4. doi: 10.1007/s10072-012-1239-y. Epub 2012 Nov 9.
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Caudal paramedian midbrain syndrome.尾侧旁正中脑综合征
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Pure midbrain infarction: clinical, radiologic, and pathophysiologic findings.纯中脑梗死:临床、影像学及病理生理学表现
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Morphological substrate for eyelid movements: innervation and structure of primate levator palpebrae superioris and orbicularis oculi muscles.眼睑运动的形态学基础:灵长类动物上睑提肌和眼轮匝肌的神经支配与结构
J Comp Neurol. 1989 Sep 1;287(1):64-81. doi: 10.1002/cne.902870106.
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Unilateral oculomotor palsy and bilateral ptosis from paramedian midbrain infarction.中脑旁正中梗死导致的单侧动眼神经麻痹和双侧上睑下垂
Arch Neurol. 1991 Sep;48(9):983-6. doi: 10.1001/archneur.1991.00530210115031.