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升主动脉健康志愿者螺旋血流、射流及壁切应力的定量正常值。

Quantitative normal values of helical flow, flow jets and wall shear stress of healthy volunteers in the ascending aorta.

机构信息

Department of Diagnostic and Interventional Radiology, University of Leipzig - Heart Centre, Leipzig, Germany.

Department of Diagnostic and Interventional Radiology, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.

出版信息

Eur Radiol. 2022 Dec;32(12):8597-8607. doi: 10.1007/s00330-022-08866-5. Epub 2022 May 25.

DOI:10.1007/s00330-022-08866-5
PMID:35612663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9705464/
Abstract

OBJECTIVES

4D flow MRI enables quantitative assessment of helical flow. We sought to generate normal values and elucidate changes of helical flow (duration, volume, length, velocities and rotational direction) and flow jet (displacement, flow angle) as well as wall shear stress (WSS).

METHODS

We assessed the temporal helical existence (TH), maximum helical volume (HV), accumulated helical volume (HV), accumulated helical volume length (HVL), maximum forward velocity (maxV), maximum circumferential velocity (maxV), rotational direction (RD) and maximum wall shear stress (WSS) as reported elsewhere using the software tool Bloodline in 86 healthy volunteers (46 females, mean age 41 ± 13 years).

RESULTS

WSS decreased by 42.1% and maxV by 55.7% across age. There was no link between age and gender regarding the other parameters.

CONCLUSION

This study provides age-dependent normal values regarding WSS and maxV and age- and gender-independent normal values regarding TH, HV, HV, HVL, RD and V.

KEY POINTS

• 4D flow provides numerous new parameters; therefore, normal values are mandatory. • Wall shear stress decreases over age. • Maximum helical forward velocity decreases over age.

摘要

目的

4D 流磁共振成像是定量评估螺旋流的一种方法。我们旨在生成正常参考值，并阐明螺旋流（持续时间、体积、长度、速度和旋转方向）和射流（位移、流动角度）以及壁面切应力（WSS）的变化。

方法

我们使用 Bloodline 软件工具评估了 86 名健康志愿者（46 名女性，平均年龄 41 ± 13 岁）的时间螺旋存在（TH）、最大螺旋体积（HV）、累积螺旋体积（HV）、累积螺旋体积长度（HVL）、最大前进速度（maxV）、最大周向速度（maxV）、旋转方向（RD）和最大壁面切应力（WSS），这些参数如前所述。

结果

WSS 随年龄下降了 42.1%，maxV 下降了 55.7%。其他参数与年龄和性别之间没有联系。

结论

本研究提供了与 WSS 和 maxV 相关的年龄依赖性正常参考值，以及与年龄和性别无关的 TH、HV、HV、HVL、RD 和 V 的正常参考值。

关键点

• 4D 流提供了许多新的参数；因此，需要制定正常参考值。

• 壁面切应力随年龄下降。

• 最大螺旋前进速度随年龄下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/bd00ae2b4451/330_2022_8866_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/0c346d286efe/330_2022_8866_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/57708afb7460/330_2022_8866_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/a107eb36c2b3/330_2022_8866_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/9ec92e7035fd/330_2022_8866_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/fe9999d4964f/330_2022_8866_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/bd00ae2b4451/330_2022_8866_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/0c346d286efe/330_2022_8866_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/57708afb7460/330_2022_8866_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/a107eb36c2b3/330_2022_8866_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/9ec92e7035fd/330_2022_8866_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/fe9999d4964f/330_2022_8866_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9705464/bd00ae2b4451/330_2022_8866_Fig6_HTML.jpg

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