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一种使用自体肝动脉的活体相关供肝肝动脉夹层的新型显微外科重建技术。

A novel microsurgical reconstruction technique in a living-related liver donor hepatic artery dissection using the native hepatic artery.

机构信息

UCSF Department of Surgery, San Francisco, California, USA.

UCSF Department of Abdominal Transplantation, San Francisco, California, USA.

出版信息

Am J Transplant. 2022 Oct;22(10):2467-2469. doi: 10.1111/ajt.17103. Epub 2022 Jun 14.

Abstract

In living donor liver transplantation, hepatic artery intimal dissection is a rare but devastating complication often resulting in the inability to utilize the graft. We detail the salvage of a dissected donor right hepatic artery utilizing the recipient hepatic artery. After removal of the right lobe, the donor artery was found to have an intimal dissection extending to multiple branches. The liver transplant surgeons requested their plastic microsurgeon colleague to assist with reconstruction. Ultimately, the native recipient hepatic artery was used as a branch graft as the caliber and branching pattern was appropriate. Back table microvascular reconstruction was performed using the explanted recipient hepatic artery branches as a graft to the four donor artery branches. Every anastomosis was assessed with intraoperative doppler; all were patent with acceptable flow characteristics. The patient did well post-operatively with post-operative ultrasounds demonstrating patency of the graft. Four months post-transplantation the patient developed two polymicrobial abscesses that were drained and resolved with normalization of liver function tests. This case highlights how collaboration with a microvascular surgeon enabled the salvage of a living donor graft when faced with a complex arterial dissection.

摘要

在活体肝移植中,肝动脉内膜夹层是一种罕见但严重的并发症,常导致移植物无法使用。我们详细介绍了利用受体肝动脉抢救夹层供肝右动脉的情况。右叶切除后,发现供体动脉有内膜夹层延伸至多个分支。肝移植外科医生请求他们的整形显微外科同事协助重建。最终,将合适口径和分支模式的固有受体肝动脉用作分支移植物。使用离体受体肝动脉分支作为移植物进行离体显微镜下血管重建,将其吻合至 4 个供体动脉分支。每个吻合口均在术中多普勒进行评估,所有吻合口均通畅,血流特征良好。患者术后恢复良好,术后超声显示移植物通畅。移植后 4 个月,患者出现两个多微生物脓肿,经引流后脓肿消退,肝功能检查恢复正常。这个病例强调了与显微外科医生合作如何在面对复杂的动脉夹层时抢救活体供体移植物。

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