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Mexiletine in a Newborn with Type 3 Long QT Syndrome: When Access is Difficult.

作者信息

Pereira Eduardo Nolla Silva, Sacilotto Luciana, Pessente Gabrielle D'Arezzo, Guirao Cinthya, Carvalho Mariana Lombardi Peres de, Pereira Alexandre da Costa, Darrieux Francisco Carlos da Costa, Scanavacca Maurício Ibrahim

机构信息

Universidade de São Paulo - Faculdade de Medicina Hospital das Clínicas - Instituto do Coração, São Paulo, SP - Brasil.

出版信息

Arq Bras Cardiol. 2022 May;118(5):989-991. doi: 10.36660/abc.20210533.

DOI:10.36660/abc.20210533
PMID:35613201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9368877/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/846f0ebfda69/0066-782X-abc-118-05-0989-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/e43b23dca481/0066-782X-abc-118-05-0989-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/6efee29d3b81/0066-782X-abc-118-05-0989-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/64924fd3a92f/0066-782X-abc-118-05-0989-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/846f0ebfda69/0066-782X-abc-118-05-0989-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/e43b23dca481/0066-782X-abc-118-05-0989-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/6efee29d3b81/0066-782X-abc-118-05-0989-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/64924fd3a92f/0066-782X-abc-118-05-0989-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c37/9368877/846f0ebfda69/0066-782X-abc-118-05-0989-gf02-en.jpg

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Mexiletine in a Newborn with Type 3 Long QT Syndrome: When Access is Difficult.美西律用于一名3型长QT综合征新生儿：在静脉通路建立困难时的应用
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本文引用的文献

1
Mexiletine infusion challenge test for neonatal long QT syndrome with 2:1 atrioventricular block.用于伴有2:1房室传导阻滞的新生儿长QT综合征的美西律输注激发试验。
J Arrhythm. 2019 Jun 17;35(4):685-688. doi: 10.1002/joa3.12209. eCollection 2019 Aug.
2
Complexity of ranolazine and phenytoin use in an infant with long QT syndrome type 3.3型长QT综合征婴儿使用雷诺嗪和苯妥英钠的复杂性。
HeartRhythm Case Rep. 2016 Oct 17;3(1):104-108. doi: 10.1016/j.hrcr.2016.10.001. eCollection 2017 Jan.
3
Clinical Aspects of Type 3 Long-QT Syndrome: An International Multicenter Study.
3型长QT综合征的临床特征：一项国际多中心研究
Circulation. 2016 Sep 20;134(12):872-82. doi: 10.1161/CIRCULATIONAHA.116.021823. Epub 2016 Aug 26.
4
Gene-Specific Therapy With Mexiletine Reduces Arrhythmic Events in Patients With Long QT Syndrome Type 3.美西律基因特异性疗法可减少3型长QT综合征患者的心律失常事件。
J Am Coll Cardiol. 2016 Mar 8;67(9):1053-1058. doi: 10.1016/j.jacc.2015.12.033.
5
SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.与3型长QT综合征和Brugada综合征重叠表型相关的SCN5A突变。
Circ J. 2014;78(5):1061-2. doi: 10.1253/circj.cj-14-0319. Epub 2014 Apr 2.
6
Arrhythmia phenotype during fetal life suggests long-QT syndrome genotype: risk stratification of perinatal long-QT syndrome.胎儿期心律失常表型提示长 QT 综合征基因型：围产期长 QT 综合征的风险分层。
Circ Arrhythm Electrophysiol. 2013 Oct;6(5):946-51. doi: 10.1161/CIRCEP.113.000618. Epub 2013 Aug 30.
7
High prevalence of genetic variants previously associated with LQT syndrome in new exome data.新外显子组数据中先前与 LQT 综合征相关的遗传变异的高发生率。
Eur J Hum Genet. 2012 Aug;20(8):905-8. doi: 10.1038/ejhg.2012.23. Epub 2012 Feb 29.
8
A novel SCN5A mutation manifests as a malignant form of long QT syndrome with perinatal onset of tachycardia/bradycardia.一种新型的SCN5A突变表现为长QT综合征的恶性形式，伴有围产期心动过速/心动过缓发作。
Cardiovasc Res. 2004 Nov 1;64(2):268-78. doi: 10.1016/j.cardiores.2004.07.007.
9
Long QT syndrome and life threatening arrhythmia in a newborn: molecular diagnosis and treatment response.新生儿长QT综合征与危及生命的心律失常：分子诊断与治疗反应
Heart. 2004 Jan;90(1):13-6. doi: 10.1136/heart.90.1.13.
10
Congenital long QT syndrome with functionally impaired atrioventricular conduction: successful treatment by mexiletine and propranolol.伴有功能受损的房室传导的先天性长QT综合征：美西律和普萘洛尔成功治疗
J Formos Med Assoc. 2002 Apr;101(4):291-3.