Maskey Suvana, Rijal Hima
Obstetrics and Gynaecology, Department of Obstetrics and Gynaecology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
J Nepal Health Res Counc. 2022 Mar 13;19(4):838-843. doi: 10.33314/jnhrc.v19i04.3919.
Studies done to determine relation of increase in Body mass index and semen parameters have shown conflicting results, some showing negative correlation others showing none. This study aimed to find out if there is any association between them in our population.
A cross-sectional study was performed in an infertility clinic in 2018/19 reviewing records from which Body mass index of male partner and results of semen analysis noted. Participants were grouped according to Body mass index; normal: 18.5-24.99 kg/m2, overweight: 25-29.99 kg/m2 and obese: >30 kg/m2. Different semen parameters such as volume, total count, concentration and motility were compared between different Body mass index groups to determine if there is any association between them.
Total 249 participants enrolled with mean Body mass index of 25.1 + 3.4 years. Semen volume decreased with increase in Body mass index (p value 0.063) and sperm count was lower in overweight and obese group compared to normal Body mass index group (p value 0.449) suggesting insignificant negative correlation of Body mass index with semen volume and sperm count. However there was insignificant weak positive correlation of Body mass index with sperm concentration and progressive motility (p value 0.668 and 0.973 respectively). Overweight persons were 3.14 times likely to have hypovolemia (OR:3.14; 95%CI: 1.51-6.53) and obese persons were 1.19 times likely to have oligospermia (OR:1.19 95% CI: 0.42-3.36) compared to persons with normal Body mass index.
Body mass index has insignificant negative correlation with semen volume and total sperm count and persons with higher Body mass index were more likely to have hypovolemia and oligospermia compared to person with normal Body mass index.
关于确定体重指数增加与精液参数之间关系的研究结果相互矛盾，一些研究显示呈负相关，另一些则显示无相关性。本研究旨在查明在我们的人群中它们之间是否存在任何关联。
2018/19年在一家不孕不育诊所进行了一项横断面研究，回顾记录中男性伴侣的体重指数和精液分析结果。参与者根据体重指数分组；正常：18.5 - 24.99kg/m²，超重：25 - 29.99kg/m²，肥胖：>30kg/m²。比较不同体重指数组之间不同的精液参数，如体积、总数、浓度和活力，以确定它们之间是否存在任何关联。
总共招募了249名参与者，平均体重指数为25.1 + 3.4岁。精液体积随着体重指数的增加而减少（p值0.063），超重和肥胖组的精子计数低于正常体重指数组（p值0.449），表明体重指数与精液体积和精子计数呈不显著的负相关。然而，体重指数与精子浓度和进行性活力呈不显著的弱正相关（分别为p值0.668和0.973）。与正常体重指数的人相比，超重者出现低血容量的可能性是其3.14倍（OR：3.14；95%CI：1.51 - 6.53），肥胖者出现少精子症的可能性是其1.19倍（OR：1.19，95%CI：0.42 - 3.36）。
体重指数与精液体积和总精子计数呈不显著的负相关，与正常体重指数的人相比，体重指数较高的人更有可能出现低血容量和少精子症。
