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The successful use of eculizumab for treatment of thrombotic microangiopathy in pediatric acute SARSCoV2 infection and multisystem inflammatory syndrome in children.

作者信息

Aurora Tarun, Joseph Noel, Bhoopalan Senthil Velan, Caniza Miguela A, Flerlage Tim, Ghafoor Saad, Hankins Jane, Hijano Diego R, Jesudas Rohith, Kirkham Justin, Martinez Hugo, Alfaro Gabriela Maron, Sharma Akshay, Hines Melissa

机构信息

Department of Clinical Education, St Jude Children's Research Hospital, Memphis, TN.

Department of Pediatrics, Clinical Education, University of Tennessee Health Science Center, Memphis, TN.

出版信息

Haematologica. 2022 Oct 1;107(10):2517-2522. doi: 10.3324/haematol.2022.280603.

DOI:10.3324/haematol.2022.280603
PMID:35615927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9521228/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1e2/9521228/ec6ea1f87f12/1072517.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1e2/9521228/8c5de2da8cfe/1072517.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1e2/9521228/ec6ea1f87f12/1072517.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1e2/9521228/8c5de2da8cfe/1072517.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d1e2/9521228/ec6ea1f87f12/1072517.fig2.jpg

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Sci Immunol. 2021 Apr 7;6(58). doi: 10.1126/sciimmunol.abg0833.
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Eur J Immunol. 2021 Jul;51(7):1652-1659. doi: 10.1002/eji.202048959. Epub 2021 Apr 10.
3
Eculizumab as an emergency treatment for adult patients with severe COVID-19 in the intensive care unit: A proof-of-concept study.
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Pediatr Blood Cancer. 2024 Jun;71(6):e30909. doi: 10.1002/pbc.30909. Epub 2024 Mar 12.
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Sex-specific differences in systemic immune responses in MIS-C children.川崎病患儿全身免疫反应的性别特异性差异。
Sci Rep. 2024 Jan 19;14(1):1720. doi: 10.1038/s41598-024-52116-1.
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The Rationale of Complement Blockade of the MCP Haplotype following Atypical Hemolytic Uremic Syndrome of Three Southeastern European Countries with a Literature Review.《三种东南欧国家非典型溶血尿毒症综合征后 MCP 单倍型补体阻断的理由:文献复习》
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