Song Quan-Mei, Zhang Xue-Cheng, Zhang Yong-Chen, Jia Hong-Ling
School of Acupuncture-moxibustion and Massage, Shandong University of Traditional Chinese Medicine, Jinan 250014, China.
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700.
Zhen Ci Yan Jiu. 2022 May 25;47(5):459-65. doi: 10.13702/j.1000-0607.20210134.
To explore the feasibility and application value of combination regularities of acupoint Houxi (SI3) in Chinese ancient times based on latent structure model.
Relevant articles about SI3 for treating various diseases with acupuncture, moxibustion, acupoint application, etc. were mainly searched from book Chinese Medical Classics (5th edition), followed by establishment of a Database of Houxi Acupoint Recipes. The Lantern 5.0 software was used to construct and analyze the latent structure model of high-frequently-used acupoints.
A total of 46 high frequently-used acupoints contained in 240 articles of 26 medical books were collected. The top 7 acupoints are Shenmai (BL62), Hegu (LI4), Qiangu (SI2), Fengchi (GB20), Jianshi (PC5), Wangu (SI4) and Quchi (LI11) in sequence. After modeling the 46 high-frequently used adjunct acupoints, 12 latent variables (Y0-Y11) and 24 latent classes were obtained by setting the cumulative coverage threshold ratio to be 95%. According to the Bayesian information criterion (BIC) measure, the model score was -2 170.68 points. Seven comprehensive clustering models were summarized up according to the latent structure. Compared with the yin meridians, the yang meridians played a more significant role. The multiple combinations of SI3 with specific acupoints provided a reference for clinical practice. The supplementary acupoints mainly distribute in the upper and lower limbs, head, face, neck, etc. and the SI3 acupoint recipes function mainly in dredging and activating meridians and collaterals, clearing away pathologic heat and wind, improving eyesight, and relieving swelling and pain.
The latent structure model is applicable in analysis of the regularities of SI3 acupoint combination for treating some diseases. Comprehensive clustering is employed to determine the primary acupoint SI3 and adjunct acupoint matching, revealing the common regularity and logical progressive relationship between the primary and secondary points, which may be helpful for teaching, clinical and scientific research.
基于潜在结构模型探讨中国古代后溪穴（SI3）配穴规律的可行性及应用价值。
主要从《中医经典（第5版）》中检索有关针刺、艾灸、穴位贴敷等运用SI3治疗各类疾病的相关文献，随后建立后溪穴方剂数据库。运用Lantern 5.0软件构建并分析高频穴位的潜在结构模型。
共收集到26部医学书籍240篇文章中包含的46个高频穴位。前7位穴位依次为申脉（BL62）、合谷（LI4）、前谷（SI2）、风池（GB20）、间使（PC5）、腕骨（SI4）和曲池（LI11）。对46个高频配穴进行建模，设置累积覆盖阈值比为95%后，得到12个潜在变量（Y0 - Y11）和24个潜在类别。根据贝叶斯信息准则（BIC）度量，模型得分-2170.68分。依据潜在结构总结出7种综合聚类模型。与阴经相比，阳经发挥的作用更显著。SI3与特定穴位的多种组合为临床实践提供了参考。配穴主要分布于上下肢、头、面、颈等部位，后溪穴方剂的作用主要为疏通经络、清热祛风、明目、消肿止痛。
潜在结构模型适用于分析SI3穴治疗某些疾病的配穴规律。采用综合聚类确定主穴SI3及配穴匹配，揭示主次穴位之间的共同规律及逻辑递进关系，可能有助于教学、临床及科研。
