Dubinsky R M, Jankovic J
Neurology. 1987 Apr;37(4):570-6. doi: 10.1212/wnl.37.4.570.
In 58 patients with progressive supranuclear palsy (PSP), 19 (32.8%) had CT, MRI, or autopsy evidence of a multi-infarct (MI) state. The clinical findings in the infarct syndrome were similar to idiopathic PSP. Five MI-PSP patients had had a stroke, four had focal dystonia, two had hemiparesis, and one had an intention tremor of recent onset. In contrast, only 5.9% (12.9% of those with CT or MRI) of 426 Parkinson's disease patients had evidence of strokes. One case of PSP studied pathologically was attributed to cerebral amyloid angiopathy.
在58例进行性核上性麻痹(PSP)患者中,19例(32.8%)有CT、MRI或尸检证据显示存在多发性梗死(MI)状态。梗死综合征的临床发现与特发性PSP相似。5例MI-PSP患者曾发生过中风,4例有局灶性肌张力障碍,2例有偏瘫,1例有近期出现的意向性震颤。相比之下,426例帕金森病患者中只有5.9%(CT或MRI检查患者中的12.9%)有中风证据。经病理研究的1例PSP病例归因于脑淀粉样血管病。