Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128 Rome, Italy.
Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128 Rome, Italy.
Psychiatry Res. 2022 Jul;313:114634. doi: 10.1016/j.psychres.2022.114634. Epub 2022 May 14.
Several studies have evaluated the level of autistic symptomatology in schizophrenia patients (SCZ) and ultra-high risk for psychosis (UHR) patients, but the data are not conclusive. Using the PANSS Autism Severity Score (PAUSS) scale, we found that the degree of autistic symptomatology in UHR patients is significantly lower compared to SCZ patients but higher than in patients with a mood disorder. Moreover, we found a significant correlation between autistic symptomatology and the severity of formal thought disorders, confirming Bleuler's hypothesis about autism and association disorders as core features of psychosis.
几项研究评估了精神分裂症患者（SCZ）和精神病超高风险（UHR）患者的自闭症症状水平，但数据尚无定论。使用 PANSS 自闭症严重程度评分（PAUSS）量表，我们发现 UHR 患者的自闭症症状程度明显低于 SCZ 患者，但高于心境障碍患者。此外，我们发现自闭症症状与形式思维障碍严重程度之间存在显著相关性，证实了 Bleuler 关于自闭症和联想障碍是精神病核心特征的假说。
