Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Anesthesiology and Intensive Care, Randers Regional Hospital, Randers, Denmark.
Resuscitation. 2022 Aug;177:69-77. doi: 10.1016/j.resuscitation.2022.05.014. Epub 2022 May 23.
To investigate how socioeconomic status was associated with the risk of in-hospital cardiac arrest in Denmark.
We conducted a matched case-control study based on data from nationwide registries in Denmark. A total of 3,449 cases with in-hospital cardiac arrest in 2017 and 2018 were matched at the index time based on age and sex with up to 10 controls from the total Danish population (background controls) and a hospitalized patient population (hospitalized controls), respectively. Household income, household assets, and education were used as measures of socioeconomic status. Conditional logistic regression was used to assess the association between socioeconomic status and the risk of in-hospital cardiac arrest.
Across all analyses of cases and controls, high household income, high household assets, and higher education were associated with decreased odds of in-hospital cardiac arrest. In the analyses of cases and background controls, high household income was associated with 0.45 (95% CI: 0.40, 0.52) times the odds of in-hospital cardiac arrest compared to low household income, which was similar for household assets. Compared to basic education, higher education was associated with 0.50 (95% CI: 0.43, 0.58) times the odds of in-hospital cardiac arrest. The results attenuated marginally after adjustment for comorbidities. Similar albeit attenuated findings were observed in the analyses of cases and hospitalized controls.
In this matched case-control study, high socioeconomic status was associated with lower odds of in-hospital cardiac arrest compared to low socioeconomic status. The findings were consistent across household income, household assets, and education and persisted after adjustment for comorbidities. Strategies are needed to address the socioeconomic inequalities observed in the risk of in-hospital cardiac arrest.
研究丹麦的社会经济地位如何与院内心脏骤停的风险相关。
我们基于丹麦全国性登记处的数据开展了一项匹配病例对照研究。共纳入了 2017 年和 2018 年 3449 例院内心脏骤停的病例，并根据年龄和性别与总丹麦人群（背景对照）和住院患者人群（住院对照）中最多 10 名对照进行了匹配。家庭收入、家庭资产和教育程度被用作社会经济地位的衡量标准。采用条件逻辑回归评估了社会经济地位与院内心脏骤停风险之间的关联。
在所有病例和对照的分析中，高家庭收入、高家庭资产和高教育程度与院内心脏骤停的风险降低相关。在病例和背景对照的分析中，与低收入家庭相比，高家庭收入与院内心脏骤停的风险降低 0.45 倍（95%CI：0.40，0.52），家庭资产的情况类似。与基础教育相比，高等教育与院内心脏骤停的风险增加 0.50 倍（95%CI：0.43，0.58）相关。在调整了合并症后，结果略有减弱。在病例和住院对照的分析中观察到了类似但略有减弱的结果。
在这项匹配病例对照研究中，与低社会经济地位相比，高社会经济地位与院内心脏骤停的风险降低相关。这些发现与家庭收入、家庭资产和教育程度有关，在调整了合并症后仍然存在。需要采取策略来解决院内心脏骤停风险中存在的社会经济不平等问题。
