Nielsen H E, Melsen F, Christensen M S
Scand J Urol Nephrol Suppl. 1977(42):127-9.
24 renal transplanted patients who developed post-transplant bone complications (aseptic necrosis of bone of spontaneous fractures) were studied and compared with a control material of age- and sexmatched renal transplanted (RT) patients. The bone mineral concentration in the forearm, histomorphometric measurements of iliac crest biopsies, and the parathyroid function were investigated. A significant reduction in the bone mineral concentration was found in the group of RT patients with bone complications compared to RT patients without. The amount of cancellous bone in the bone biopsies was reduced in patients with aseptic necrosis of bone. No significant differences in the biochemical values were found.
对24例发生移植后骨并发症（无菌性骨坏死或自发性骨折）的肾移植患者进行了研究，并与年龄和性别匹配的肾移植（RT）对照患者进行了比较。研究了前臂骨矿物质浓度、髂嵴活检的组织形态计量学测量结果以及甲状旁腺功能。与无骨并发症的肾移植患者相比，有骨并发症的肾移植患者组的骨矿物质浓度显著降低。骨活检中松质骨量在无菌性骨坏死患者中减少。生化值未发现显著差异。
