Nielsen H E
Clin Nephrol. 1978 Nov;10(5):196-200.
Bone mineral content (BMC) in the forearm was measured in 158 renal transplant patients to elucidate the relationship between bone mass and the development of bone lesions following renal transplantation. In renal transplant patients with aseptic necrosis of bone and with spontaneous fractures the BMC was significantly reduced compared with age and sex matched renal transplant control patients. Other factors connected with low BMC were age, sex, prolonged dialysis prior to transplantation, post-transplant hypercalcemia and elevated serum alkaline phosphatase at the time of the study. No relation between BMC and duration of immunosuppressive treatment was demonstrated.
对158例肾移植患者测量了前臂骨矿物质含量(BMC),以阐明肾移植后骨量与骨病变发展之间的关系。与年龄和性别匹配的肾移植对照患者相比,发生无菌性骨坏死和自发性骨折的肾移植患者的BMC显著降低。与低BMC相关的其他因素包括年龄、性别、移植前长期透析、移植后高钙血症以及研究时血清碱性磷酸酶升高。未证明BMC与免疫抑制治疗持续时间之间存在关联。