• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

丁香酚治疗脑部疾病的治疗潜力的临床前循证综述

Preclinical Evidence-based Review on Therapeutic Potential of Eugenol for the Treatment of Brain Disorders.

作者信息

Goyal Ahsas, Solanki Ashutosh, Verma Aanchal

机构信息

Department of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, U.P., India.

出版信息

Curr Mol Med. 2023;23(5):390-400. doi: 10.2174/1566524022666220525145521.

DOI:10.2174/1566524022666220525145521
PMID:35619280
Abstract

The increasing morbidness of brain disorders and conditions, such as anxiety, stress, depression, Alzheimer's disease, Parkinson's disease, and others, have become severe. Although researchers have spent a significant amount of time examining these diseases and providing many benefits, there are still limited drugs available to treat these disorders. Eugenol, a dietary component present in numerous plants and herbs, possesses various health benefits. In various preclinical studies, eugenol has provided significant protective effects against a variety of brain disorders. Thus, including eugenol in the diet can fight various diseases and ensure a healthy life. Considering the fruitful impact of this compound, this review focuses on the brain disorders in which eugenol was used, and summarizes the beneficial properties of eugenol and its role in treating various brain diseases.

摘要

诸如焦虑、压力、抑郁、阿尔茨海默病、帕金森病等脑部疾病和病症的发病率不断上升,情况已变得很严重。尽管研究人员花费了大量时间研究这些疾病并取得了诸多成果,但用于治疗这些病症的药物仍然有限。丁香酚是众多植物和草药中含有的一种膳食成分,具有多种健康益处。在各种临床前研究中,丁香酚对多种脑部疾病都具有显著的保护作用。因此,在饮食中摄入丁香酚可以对抗各种疾病并确保健康生活。鉴于这种化合物的显著效果,本综述聚焦于使用丁香酚治疗的脑部疾病,并总结了丁香酚的有益特性及其在治疗各种脑部疾病中的作用。

相似文献

1
Preclinical Evidence-based Review on Therapeutic Potential of Eugenol for the Treatment of Brain Disorders.丁香酚治疗脑部疾病的治疗潜力的临床前循证综述
Curr Mol Med. 2023;23(5):390-400. doi: 10.2174/1566524022666220525145521.
2
Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease.柚皮素:一种用于治疗阿尔茨海默病和帕金森病的潜在治疗药物。
J Food Biochem. 2022 Dec;46(12):e14415. doi: 10.1111/jfbc.14415. Epub 2022 Sep 15.
3
Unraveling Amentoflavone's Therapeutic Potential in Alzheimer's Disease: A Preclinical Assessment.解析阿魏酸的阿尔茨海默病治疗潜力:一项临床前评估。
Comb Chem High Throughput Screen. 2024;27(13):1851-1860. doi: 10.2174/0113862073301291240229102657.
4
Eugenol Elicits Prolongevity by Increasing Resistance to Oxidative Stress in C. elegans.丁香酚通过增加秀丽隐杆线虫对氧化应激的抵抗力来延长寿命。
CNS Neurol Disord Drug Targets. 2022;21(9):841-853. doi: 10.2174/1871527320666211008150347.
5
Therapeutic Potential of Baicalein in Alzheimer's Disease and Parkinson's Disease.黄芩素在阿尔茨海默病和帕金森病中的治疗潜力
CNS Drugs. 2017 Aug;31(8):639-652. doi: 10.1007/s40263-017-0451-y.
6
Effects of eugenol on the behavioral and pathological progression in the MPTP-induced Parkinson's disease mouse model.丁香酚对 MPTP 诱导的帕金森病小鼠模型行为和病理进展的影响。
Drug Discov Ther. 2022 Sep 17;16(4):154-163. doi: 10.5582/ddt.2022.01026. Epub 2022 Aug 24.
7
Effects of zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] and eugenol [2-methoxy-4-(2-propenyl)phenol] on the pathological progress in the 6-hydroxydopamine-induced Parkinson's disease mouse model.荜澄茄酮[4-(4-羟基-3-甲氧基苯基)-2-丁酮]和丁香酚[2-甲氧基-4-(2-丙烯基)苯酚]对 6-羟多巴胺诱导的帕金森病小鼠模型中病理进程的影响。
Neurochem Res. 2011 Dec;36(12):2244-9. doi: 10.1007/s11064-011-0548-5. Epub 2011 Jul 19.
8
Antioxidant properties of eugenol, butylated hydroxylanisole, and butylated hydroxyl toluene with key biomolecules relevant to Alzheimer's diseases-In vitro.丁香酚、叔丁基对羟基茴香醚和叔丁基对羟基甲苯与关键生物分子的抗氧化性能在阿尔茨海默病中的体外研究。
J Food Biochem. 2021 Mar;45(3):e13276. doi: 10.1111/jfbc.13276. Epub 2020 May 26.
9
Eugenol and its association with levodopa in 6-hydroxydopamine-induced hemiparkinsonian rats: Behavioural and neurochemical alterations.丁香酚及其与左旋多巴在 6-羟多巴胺诱导的半帕金森病大鼠中的联合作用:行为和神经化学改变。
Basic Clin Pharmacol Toxicol. 2020 Oct;127(4):287-302. doi: 10.1111/bcpt.13425. Epub 2020 May 15.
10
Eugenol as a Potential Drug Candidate: A Review.丁香酚作为一种潜在的候选药物:综述
Curr Top Med Chem. 2021;21(20):1804-1815. doi: 10.2174/1568026621666210701141433.

引用本文的文献

1
Syzygium aromaticum L. (Clove): A Comprehensive Reveiw of Its Ethnopharmacological Uses and Pharmacological Activities.丁香(Syzygium aromaticum L.):其民族药理学用途和药理活性的综合综述
Chin J Integr Med. 2025 Aug 15. doi: 10.1007/s11655-025-4141-1.
2
Exploring the neuroprotective role of (Shatavari) in Alzheimer's disease: mechanisms, evidence, and future directions.探索印度人参在阿尔茨海默病中的神经保护作用:机制、证据及未来方向。
3 Biotech. 2025 Jul;15(7):197. doi: 10.1007/s13205-025-04355-w. Epub 2025 May 30.
3
Neuroprotective effects of flavonoids: endoplasmic reticulum as the target.
类黄酮的神经保护作用:以内质网为靶点。
Front Neurosci. 2024 Jun 18;18:1348151. doi: 10.3389/fnins.2024.1348151. eCollection 2024.
4
Therapeutic Potential of Capsaicin in Various Neurodegenerative Diseases with Special Focus on Nrf2 Signaling.辣椒素在各种神经退行性疾病中的治疗潜力,特别关注 Nrf2 信号通路。
Curr Pharm Biotechnol. 2024;25(13):1693-1707. doi: 10.2174/0113892010277933231122111244.
5
Recordings in an integrating central neuron reveal the mode of action of isoeugenol.整合中枢神经元的记录揭示了异丁香酚的作用模式。
Commun Biol. 2023 Mar 23;6(1):309. doi: 10.1038/s42003-023-04695-4.