玻璃体内注射α-干扰素的毒性
Toxicity of intravitreally administered alpha-interferon.
作者信息
Dharma S K, Peyman G A, Vernot J, Fiscella R
出版信息
Ophthalmic Surg. 1987 Jan;18(1):51-4.
PMID:3561938
Abstract
We studied the toxicity of single doses of intravitreally administered alpha-interferon in albino rabbits. Doses of 420,000, 210,000, 105,000, 52,500, and 26,250 units/0.1 cc showed no significant histologic changes by light microscopy or altered retinal function assessed by photopic and scotopic electroretinography.
摘要
我们研究了玻璃体内单次注射α-干扰素对白化兔的毒性。剂量为420,000、210,000、105,000、52,500和26,250单位/0.1立方厘米时，通过光学显微镜检查未发现明显的组织学变化，且明视和暗视视网膜电图评估的视网膜功能也未改变。
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