沃夫勒姆综合征中的视神经萎缩。

Optic atrophy in Wolfram syndrome.

作者信息

Mtanda A T, Cruysberg J R, Pinckers A J

出版信息

Ophthalmic Paediatr Genet. 1986 Dec;7(3):159-65. doi: 10.3109/13816818609004133.

PMID:3561950

Abstract

The clinical and electrophysiologic findings in 11 cases of Wolfram syndrome are presented. These findings suggest that optic atrophy in Wolfram syndrome is not secondary to retinal pathology, but probably represents part of a generalized degeneration of neural structures. The relationship of diabetes mellitus to this process of neural degeneration remains unclear.

摘要

本文报告了11例沃夫勒姆综合征的临床和电生理检查结果。这些结果表明，沃夫勒姆综合征中的视神经萎缩并非继发于视网膜病变，而可能是神经结构广泛性退变的一部分。糖尿病与这种神经退变过程之间的关系仍不清楚。