Van den Bergh L, Zeyen T, Verhelst J, Mahler C
Department of Ophthalmology, Middelheimziekenhuis, Antwerp, Belgium.
Doc Ophthalmol. 1993;84(2):119-26. doi: 10.1007/BF01206246.
Two unrelated patients with two different images of Wolfram (or 'DIDMOAD') syndrome are presented: a 19-year old woman suffering from all the important features of this syndrome, and a 38-year old man showing two major characteristics but several minor abnormalities. This syndrome should be considered in young diabetic patients with unexplained visual loss or with polyuria and polydipsia in the presence of adequate blood sugar control. An early diagnosis is important to prevent unnecessary diagnostic investigations.
本文介绍了两名患有不同症状的沃夫勒姆（或“DIDMOAD”）综合征患者：一名19岁女性，患有该综合征的所有主要症状；一名38岁男性，表现出两个主要特征，但有一些轻微异常。对于血糖控制良好但出现不明原因视力丧失或多尿、烦渴的年轻糖尿病患者，应考虑该综合征。早期诊断对于避免不必要的诊断检查很重要。
