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肾细胞癌合并下腔静脉瘤栓,最初因高凝状态被误诊为单纯血栓。

Renal cell carcinoma with inferior vena cava tumor thrombus initially misdiagnosed as bland thrombus due to hypercoagulable state.

作者信息

Tabbara Marina M, Farag Ahmed, Ciancio Gaetano

机构信息

Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.

Miami Transplant Institute, Miller School of Medicine, University of Miami, Jackson Memorial Hospital, Miami, FL, USA.

出版信息

SAGE Open Med Case Rep. 2022 May 21;10:2050313X221102019. doi: 10.1177/2050313X221102019. eCollection 2022.

DOI:10.1177/2050313X221102019
PMID:35619748
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9128047/
Abstract

Renal cell carcinoma with inferior vena cava tumor thrombus can be misdiagnosed as an inferior vena cava thrombosis if not evaluated carefully with imaging. We describe a case of renal cell carcinoma with inferior vena cava tumor thrombus that was initially misdiagnosed as an inferior vena cava thrombosis due to a possible hypercoagulable state. After 7 months of anticoagulation therapy with no improvement, a right radical nephrectomy and thrombectomy was performed without cardiopulmonary bypass, and a diagnosis of papillary renal cell carcinoma with a level-IIId tumor thrombus was confirmed with no presence of a bland thrombus. We demonstrate the complexity of identifying and treating renal cell carcinoma with venous tumor thrombus and the importance of differentiating between a malignant thrombus and a bland thrombus.

摘要

肾细胞癌合并下腔静脉瘤栓如果不通过影像学仔细评估,可能会被误诊为下腔静脉血栓形成。我们描述了一例肾细胞癌合并下腔静脉瘤栓的病例,该病例最初因可能存在的高凝状态而被误诊为下腔静脉血栓形成。在进行了7个月的抗凝治疗且无改善后,在未进行体外循环的情况下实施了右肾根治性切除术和血栓切除术,最终确诊为伴有Ⅲd级瘤栓的乳头状肾细胞癌,不存在单纯性血栓。我们展示了识别和治疗伴有静脉瘤栓的肾细胞癌的复杂性,以及区分恶性血栓和单纯性血栓的重要性。

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本文引用的文献

1
Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus in Two Patients With Previous Coronary Artery Bypass Graft: Strategy for Surgical Removal.两名曾接受冠状动脉旁路移植术的患者合并肾细胞癌伴下腔静脉肿瘤血栓:手术切除策略
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Epidemiology of Renal Cell Carcinoma.肾细胞癌的流行病学
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腹部和骨盆中的静脉血栓形成和高凝状态:病因和影像学表现。
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Surgical Treatment Strategy with Combined Cardiopulmonary Bypass for Renal Cell Carcinoma with Tumor Embolism Developed in Inferior Vena Cava.采用体外循环联合治疗下腔静脉内出现肿瘤栓子的肾细胞癌的手术治疗策略
Heart Surg Forum. 2020 Feb 10;23(1):E025-E029. doi: 10.1532/hsf.2741.
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Association of an organ transplant-based approach with a dramatic reduction in postoperative complications following radical nephrectomy and tumor thrombectomy in renal cell carcinoma.基于器官移植的方法与肾细胞癌根治性肾切除术和肿瘤栓子切除术术后并发症显著减少相关。
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7
Renal Cell Carcinoma With Extensive Tumor Thrombus Into the Inferior Vena Cava and Right Atrium in a 70-Year-Old Man.70 岁男性,肾细胞癌伴下腔静脉及右心房广泛癌栓。
Am J Mens Health. 2019 May-Jun;13(3):1557988319846404. doi: 10.1177/1557988319846404.
8
The role of transesophageal echocardiography in the management of renal cell carcinoma with venous tumor thrombus.经食管超声心动图在肾细胞癌伴静脉瘤栓管理中的作用
Echocardiography. 2018 Dec;35(12):2047-2055. doi: 10.1111/echo.14187. Epub 2018 Nov 1.
9
Tumor thrombus: incidence, imaging, prognosis and treatment.肿瘤血栓:发病率、影像学、预后及治疗
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Surgical technique for the treatment of renal cell carcinoma with inferior vena cava tumor thrombus: tips, tricks and oncological results.治疗伴下腔静脉瘤栓的肾细胞癌的手术技术:技巧、窍门及肿瘤学结果
Springerplus. 2016 Feb 20;5:132. doi: 10.1186/s40064-016-1825-1. eCollection 2016.