Delayed renal and extrarenal complications following primarily successful renal transplantation.

Delayed renal and extrarenal complications after primarily completely successful renal transplantations is surveyed. All cases in which a surgical or clinical complication, a rejection or a complication of the immunosuppressive treatment had occurred were omitted. Primarily, 84 out of 476 transplantations (17%) were completely successful. After six months, the continued course was entirely uneventful in 47 of these cases. In 37 some kind of renal and/or extrarenal complication occurred 6-114 months after the primarily successful course. The complications could not be correlated to histocompatibility, sex, age or basic disease. During the last years, when the basic immunosuppressive treatment was reduced and principally alternative day treatment of corticosteroids was used, the complications diminished.